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Building evidence for improving childhood immunisation coverage in Africa.
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Clinical Laboratory Sciences
2014
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| _version_ | 1867613487529721856 |
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| access_status_str | Open Access |
| author | Wiysonge, Shey Umaru Charles |
| author2 | Hussey, Gregory D |
| author_browse | Hussey, Gregory D Wiysonge, Shey Umaru Charles |
| author_facet | Hussey, Gregory D Wiysonge, Shey Umaru Charles |
| author_sort | Wiysonge, Shey Umaru Charles |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3183 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:36:56.031Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Clinical Laboratory Sciences |
| publisherStr | Department of Clinical Laboratory Sciences |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3183 Building evidence for improving childhood immunisation coverage in Africa. Wiysonge, Shey Umaru Charles Hussey, Gregory D Schoub, Barry D Clinical Laboratory Sciences Includes abstract. Includes bibliographical references. The Expanded Programme on Immunisation has the potential to substantially reduce child mortality and contribute to achieving the Millennium Development Goals. We assessed the programme’s performance in Africa, the reasons for poor performance, and effective interventions for improving its performance on the continent. We used a combination of methods including systematic reviews, bibliometric analyses, generalised linear models, and grading of the quality of evidence. We found that African countries have made extraordinary advances since childhood immunisation programmes began in 1974. However, there exist wide inter-country and intra-country differences, and the quality of immunisation data is poor. Besides, vaccines are administered well after the recommended ages in many countries; leaving children exposed to deadly vaccine-preventable diseases for long periods. In addition, Africa’s contribution to the global immunisation research output is minimal. There is no association between research productivity and immunisation coverage in Africa, which may signal lack of interactive communication between policymakers and researchers. Furthermore, individual and contextual factors (defined at community and country levels) are independently associated with low immunisation coverage; suggesting that immunisation system strengthening should address people and the communities and societies in which they live. Lastly, we found moderate-to-high quality evidence that interactive educational meetings, audit and feedback, supportive supervision; and use of community health workers, parent reminders, home visits, interactive communication, mass media, and material incentives have the potential to improve childhood immunisation coverage in Africa. 2014-07-28T14:58:33Z 2014-07-28T14:58:33Z 2012 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3183 eng application/pdf Department of Clinical Laboratory Sciences Faculty of Health Sciences University of Cape Town |
| spellingShingle | Clinical Laboratory Sciences Wiysonge, Shey Umaru Charles Building evidence for improving childhood immunisation coverage in Africa. |
| thesis_degree_str | Doctoral |
| title | Building evidence for improving childhood immunisation coverage in Africa. |
| title_full | Building evidence for improving childhood immunisation coverage in Africa. |
| title_fullStr | Building evidence for improving childhood immunisation coverage in Africa. |
| title_full_unstemmed | Building evidence for improving childhood immunisation coverage in Africa. |
| title_short | Building evidence for improving childhood immunisation coverage in Africa. |
| title_sort | building evidence for improving childhood immunisation coverage in africa |
| topic | Clinical Laboratory Sciences |
| url | http://hdl.handle.net/11427/3183 |
| work_keys_str_mv | AT wiysongesheyumarucharles buildingevidenceforimprovingchildhoodimmunisationcoverageinafrica |