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African mole rats as models for regressive evolution of the eye
Includes bibliographical references (leaves 152-166).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Department of Human Biology
2014
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| _version_ | 1867613245474340864 |
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| access_status_str | Open Access |
| author | Nikitina, Natalya |
| author2 | Kidson, Sue H |
| author_browse | Kidson, Sue H Nikitina, Natalya |
| author_facet | Kidson, Sue H Nikitina, Natalya |
| author_sort | Nikitina, Natalya |
| collection | Thesis |
| description | Includes bibliographical references (leaves 152-166). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3187 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:05.164Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Human Biology |
| publisherStr | Department of Human Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3187 African mole rats as models for regressive evolution of the eye Nikitina, Natalya Kidson, Sue H Medicine Includes bibliographical references (leaves 152-166). Darkness-adapted mammals with reduced eyes can serve as valuable models for the study of regressive evolution, as well as for research into the genetic and developmental processes underlying the "degeneration" of the eye. The aim of this work was to characterize two African mole rate species (Heterocephalus glaber and Bathyergus suillus) and explore their potential use as novel models for evolutionary developmental eye research. To this end, this histological structure of the adult eye, the development of the eye and the expression of several molecular markers were investigated. The important abnormal features noted were: the abnormal shape and nuclear distribution in the lens, the extremely large ciliary body and delay in the formation of the anterior chamber compared to other ocular structures. 2014-07-28T18:14:06Z 2014-07-28T18:14:06Z 2006 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3187 eng application/pdf Department of Human Biology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Nikitina, Natalya African mole rats as models for regressive evolution of the eye |
| thesis_degree_str | Doctoral |
| title | African mole rats as models for regressive evolution of the eye |
| title_full | African mole rats as models for regressive evolution of the eye |
| title_fullStr | African mole rats as models for regressive evolution of the eye |
| title_full_unstemmed | African mole rats as models for regressive evolution of the eye |
| title_short | African mole rats as models for regressive evolution of the eye |
| title_sort | african mole rats as models for regressive evolution of the eye |
| topic | Medicine |
| url | http://hdl.handle.net/11427/3187 |
| work_keys_str_mv | AT nikitinanatalya africanmoleratsasmodelsforregressiveevolutionoftheeye |