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The genetic relationship between the serologically detectable antigens of the HLA-A and B loci and the mixed lymphocyte culture (MLC) reaction is of utmost importance in the understanding of histocompatibility. From the literature it appeared that neither the HLA-A, B genotype nor the MLC reaction...
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| Format: | Thesis |
| Language: | English |
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Adolescent Health Research Institute
2020
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| _version_ | 1867614184501411840 |
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| access_status_str | Open Access |
| author | du Toit, Ernette D |
| author_browse | du Toit, Ernette D |
| author_facet | du Toit, Ernette D |
| author_sort | du Toit, Ernette D |
| collection | Thesis |
| description | The genetic relationship between the serologically detectable antigens of the HLA-A and B loci and the mixed
lymphocyte culture (MLC) reaction is of utmost importance in the understanding of histocompatibility. From the literature it appeared that neither the HLA-A, B genotype nor the MLC reaction is the complete answer to donorrecipient selection in organ transplantation. This study was therefore initiated in June 1971 in an attempt to clarify the problem. It is inherent in a project of this nature that much time is spent in collecting samples from donors in diverse areas. Most experiments had to be repeated two or three times, therefore some of the problems we set out to resolve were clarified by other workers before we were able to complete our investigations. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/31922 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:48:00.715Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Adolescent Health Research Institute |
| publisherStr | Adolescent Health Research Institute |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/31922 Investigations of the Genetic aspects of the mixed Lymphocyte culture reaction in Southern Africa du Toit, Ernette D Lymphocyte culture Leukocyte antigens The genetic relationship between the serologically detectable antigens of the HLA-A and B loci and the mixed lymphocyte culture (MLC) reaction is of utmost importance in the understanding of histocompatibility. From the literature it appeared that neither the HLA-A, B genotype nor the MLC reaction is the complete answer to donorrecipient selection in organ transplantation. This study was therefore initiated in June 1971 in an attempt to clarify the problem. It is inherent in a project of this nature that much time is spent in collecting samples from donors in diverse areas. Most experiments had to be repeated two or three times, therefore some of the problems we set out to resolve were clarified by other workers before we were able to complete our investigations. 2020-05-19T11:20:19Z 2020-05-19T11:20:19Z 1978 2020-04-16T07:14:35Z Doctoral Thesis Doctoral https://hdl.handle.net/11427/31922 eng application/pdf Adolescent Health Research Institute Faculty of Health Sciences |
| spellingShingle | Lymphocyte culture Leukocyte antigens du Toit, Ernette D Investigations of the Genetic aspects of the mixed Lymphocyte culture reaction in Southern Africa |
| thesis_degree_str | Doctoral |
| title | Investigations of the Genetic aspects of the mixed Lymphocyte culture reaction in Southern Africa |
| title_full | Investigations of the Genetic aspects of the mixed Lymphocyte culture reaction in Southern Africa |
| title_fullStr | Investigations of the Genetic aspects of the mixed Lymphocyte culture reaction in Southern Africa |
| title_full_unstemmed | Investigations of the Genetic aspects of the mixed Lymphocyte culture reaction in Southern Africa |
| title_short | Investigations of the Genetic aspects of the mixed Lymphocyte culture reaction in Southern Africa |
| title_sort | investigations of the genetic aspects of the mixed lymphocyte culture reaction in southern africa |
| topic | Lymphocyte culture Leukocyte antigens |
| url | https://hdl.handle.net/11427/31922 |
| work_keys_str_mv | AT dutoiternetted investigationsofthegeneticaspectsofthemixedlymphocyteculturereactioninsouthernafrica |