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A study comparing the effects of vincristine with those of ionizing radiation on the root meristem of Vicia faba
Vincristine and vinblastine, two closely related alkaloids are extracted from the Madagaskar Periwinkle, Vinca rosea Linn. They have been shown to be effective oncolytic agents and cause arrest of mitosis at the metaphase stage, similar to that of colchicine andcolcimid. Clinically, vincristine has...
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| Format: | Thesis |
| Language: | English |
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Department of Human Biology
2020
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| _version_ | 1867613245475389440 |
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| access_status_str | Open Access |
| author | Haddad, Dawne Merle |
| author_browse | Haddad, Dawne Merle |
| author_facet | Haddad, Dawne Merle |
| author_sort | Haddad, Dawne Merle |
| collection | Thesis |
| description | Vincristine and vinblastine, two closely related alkaloids are extracted from the Madagaskar Periwinkle, Vinca rosea Linn. They have been shown to be effective oncolytic agents and cause arrest of mitosis at the metaphase stage, similar to that of colchicine andcolcimid. Clinically, vincristine has been found to produce a complete remission in patients with acute leukaemia. Tumour regression in patients with Hodgkin's disease, lymphosarcoma and certain childhood solid tumours have also been reported. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/31950 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:05.164Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Department of Human Biology |
| publisherStr | Department of Human Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/31950 A study comparing the effects of vincristine with those of ionizing radiation on the root meristem of Vicia faba Haddad, Dawne Merle Meristem Radiation effects Vincristine and vinblastine, two closely related alkaloids are extracted from the Madagaskar Periwinkle, Vinca rosea Linn. They have been shown to be effective oncolytic agents and cause arrest of mitosis at the metaphase stage, similar to that of colchicine andcolcimid. Clinically, vincristine has been found to produce a complete remission in patients with acute leukaemia. Tumour regression in patients with Hodgkin's disease, lymphosarcoma and certain childhood solid tumours have also been reported. 2020-05-20T22:00:02Z 2020-05-20T22:00:02Z 1972 2020-04-07T07:26:38Z Master Thesis Masters https://hdl.handle.net/11427/31950 eng application/pdf Department of Human Biology Faculty of Health Sciences |
| spellingShingle | Meristem Radiation effects Haddad, Dawne Merle A study comparing the effects of vincristine with those of ionizing radiation on the root meristem of Vicia faba |
| thesis_degree_str | Master's |
| title | A study comparing the effects of vincristine with those of ionizing radiation on the root meristem of Vicia faba |
| title_full | A study comparing the effects of vincristine with those of ionizing radiation on the root meristem of Vicia faba |
| title_fullStr | A study comparing the effects of vincristine with those of ionizing radiation on the root meristem of Vicia faba |
| title_full_unstemmed | A study comparing the effects of vincristine with those of ionizing radiation on the root meristem of Vicia faba |
| title_short | A study comparing the effects of vincristine with those of ionizing radiation on the root meristem of Vicia faba |
| title_sort | study comparing the effects of vincristine with those of ionizing radiation on the root meristem of vicia faba |
| topic | Meristem Radiation effects |
| url | https://hdl.handle.net/11427/31950 |
| work_keys_str_mv | AT haddaddawnemerle astudycomparingtheeffectsofvincristinewiththoseofionizingradiationontherootmeristemofviciafaba AT haddaddawnemerle studycomparingtheeffectsofvincristinewiththoseofionizingradiationontherootmeristemofviciafaba |