Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Biochemical studies in drug-induced porphyrias in the rat : with a review of the literature on experimental porphyria and an investigation of thirteen human cases
The group of disorders characterized by disturbances of porphyrin metabolism pose .many fascinating problems. The drug-induced porphyrias in animals provide a model whereby these problems may be investigated by techniques which cannot be applied to man. The consumption of alcoholic beverages or othe...
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Integrative Biomedical Sciences (IBMS)
2020
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867611340462358528 |
|---|---|
| access_status_str | Open Access |
| author | Ginsburg, Aubrey David |
| author_browse | Ginsburg, Aubrey David |
| author_facet | Ginsburg, Aubrey David |
| author_sort | Ginsburg, Aubrey David |
| collection | Thesis |
| description | The group of disorders characterized by disturbances of porphyrin metabolism pose .many fascinating problems. The drug-induced porphyrias in animals provide a model whereby these problems may be investigated by techniques which cannot be applied to man. The consumption of alcoholic beverages or other chemical substances has been associated with the development of porphyrinuria and porphyria, but it is controversial whether these agents are of primary aetiological importance. or 'Whether they precipitate the· disease in genetically predisposed individuals.
The Turkish epidemic of porphyrla has shown conclusively·that this disease may occur as an acquired condition in man.
and a variety of compounds has been shown to be capable of inducing porphyria in animals. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/31967 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Department of Integrative Biomedical Sciences (IBMS) |
| publisherStr | Department of Integrative Biomedical Sciences (IBMS) |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/31967 Biochemical studies in drug-induced porphyrias in the rat : with a review of the literature on experimental porphyria and an investigation of thirteen human cases Ginsburg, Aubrey David porphyria The group of disorders characterized by disturbances of porphyrin metabolism pose .many fascinating problems. The drug-induced porphyrias in animals provide a model whereby these problems may be investigated by techniques which cannot be applied to man. The consumption of alcoholic beverages or other chemical substances has been associated with the development of porphyrinuria and porphyria, but it is controversial whether these agents are of primary aetiological importance. or 'Whether they precipitate the· disease in genetically predisposed individuals. The Turkish epidemic of porphyrla has shown conclusively·that this disease may occur as an acquired condition in man. and a variety of compounds has been shown to be capable of inducing porphyria in animals. 2020-05-21T21:33:49Z 2020-05-21T21:33:49Z 1964 2020-04-06T16:58:10Z Master Thesis Masters https://hdl.handle.net/11427/31967 eng application/pdf Department of Integrative Biomedical Sciences (IBMS) Faculty of Health Sciences |
| spellingShingle | porphyria Ginsburg, Aubrey David Biochemical studies in drug-induced porphyrias in the rat : with a review of the literature on experimental porphyria and an investigation of thirteen human cases |
| thesis_degree_str | Master's |
| title | Biochemical studies in drug-induced porphyrias in the rat : with a review of the literature on experimental porphyria and an investigation of thirteen human cases |
| title_full | Biochemical studies in drug-induced porphyrias in the rat : with a review of the literature on experimental porphyria and an investigation of thirteen human cases |
| title_fullStr | Biochemical studies in drug-induced porphyrias in the rat : with a review of the literature on experimental porphyria and an investigation of thirteen human cases |
| title_full_unstemmed | Biochemical studies in drug-induced porphyrias in the rat : with a review of the literature on experimental porphyria and an investigation of thirteen human cases |
| title_short | Biochemical studies in drug-induced porphyrias in the rat : with a review of the literature on experimental porphyria and an investigation of thirteen human cases |
| title_sort | biochemical studies in drug induced porphyrias in the rat with a review of the literature on experimental porphyria and an investigation of thirteen human cases |
| topic | porphyria |
| url | https://hdl.handle.net/11427/31967 |
| work_keys_str_mv | AT ginsburgaubreydavid biochemicalstudiesindruginducedporphyriasintheratwithareviewoftheliteratureonexperimentalporphyriaandaninvestigationofthirteenhumancases |