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Hyaline membrane disease: a study of lung function and treatment
At present, both the aetiology of hyaline membrane disease and a means of preventing it remain unknown. Recent studies indicate that a significant number of infants die of respiratory failure but there is no general agreement concerning the changes of pulmonary function which lead to this stage. Two...
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| Format: | Thesis |
| Language: | English |
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Department of Paediatrics and Child Health
2020
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| _version_ | 1867614033601888256 |
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| access_status_str | Open Access |
| author | Harrison, V C |
| author_browse | Harrison, V C |
| author_facet | Harrison, V C |
| author_sort | Harrison, V C |
| collection | Thesis |
| description | At present, both the aetiology of hyaline membrane disease and a means of preventing it remain unknown. Recent studies indicate that a significant number of infants die of respiratory failure but there is no general agreement concerning the changes of pulmonary function which lead to this stage. Two approaches have been used in the treatment of respiratory decompensation. First it has been proposed that blood gas and acid base abnormalities which result from respiratory failure can be prevented by oxygen and intravenous alkali and secondly an attempt has been made to correct abnormal lung function itself by means of artificial ventilation. These methods are directed at different aspects of the problem and their efficacy is as yet not established. The application of artificial ventilation in particular must depend on the nature of any ventilation, diffusion or perfusion defect. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/32009 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:45:36.806Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Department of Paediatrics and Child Health |
| publisherStr | Department of Paediatrics and Child Health |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/32009 Hyaline membrane disease: a study of lung function and treatment Harrison, V C Hyaline membrane disease infancy childhood Therapy At present, both the aetiology of hyaline membrane disease and a means of preventing it remain unknown. Recent studies indicate that a significant number of infants die of respiratory failure but there is no general agreement concerning the changes of pulmonary function which lead to this stage. Two approaches have been used in the treatment of respiratory decompensation. First it has been proposed that blood gas and acid base abnormalities which result from respiratory failure can be prevented by oxygen and intravenous alkali and secondly an attempt has been made to correct abnormal lung function itself by means of artificial ventilation. These methods are directed at different aspects of the problem and their efficacy is as yet not established. The application of artificial ventilation in particular must depend on the nature of any ventilation, diffusion or perfusion defect. 2020-05-29T12:51:06Z 2020-05-29T12:51:06Z 1967 2020-04-07T07:38:42Z Doctoral Thesis Doctoral https://hdl.handle.net/11427/32009 eng application/pdf Department of Paediatrics and Child Health Faculty of Health Sciences |
| spellingShingle | Hyaline membrane disease infancy childhood Therapy Harrison, V C Hyaline membrane disease: a study of lung function and treatment |
| thesis_degree_str | Doctoral |
| title | Hyaline membrane disease: a study of lung function and treatment |
| title_full | Hyaline membrane disease: a study of lung function and treatment |
| title_fullStr | Hyaline membrane disease: a study of lung function and treatment |
| title_full_unstemmed | Hyaline membrane disease: a study of lung function and treatment |
| title_short | Hyaline membrane disease: a study of lung function and treatment |
| title_sort | hyaline membrane disease a study of lung function and treatment |
| topic | Hyaline membrane disease infancy childhood Therapy |
| url | https://hdl.handle.net/11427/32009 |
| work_keys_str_mv | AT harrisonvc hyalinemembranediseaseastudyoflungfunctionandtreatment |