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For a number of years a history of sudden onset of coma, followed later by death, was noted amongst Africans at King Edward VIII hospital, Durban. Necropsy, where performed, revealed no cause in many of these patients. In 1957 after cerebrospinal fluid had been examined in some of the cases it was s...
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| Format: | Thesis |
| Language: | English |
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Department of Medicine
2020
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| _version_ | 1867613241201393664 |
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| access_status_str | Open Access |
| author | Naeme, Peter Brereton |
| author_browse | Naeme, Peter Brereton |
| author_facet | Naeme, Peter Brereton |
| author_sort | Naeme, Peter Brereton |
| collection | Thesis |
| description | For a number of years a history of sudden onset of coma, followed later by death, was noted amongst Africans at King Edward VIII hospital, Durban. Necropsy, where performed, revealed no cause in many of these patients. In 1957 after cerebrospinal fluid had been examined in some of the cases it was seen that the only abnormality present was a low cerebrospinal sugar. Hypoglycaemia was suspected and blood sugar estimation confirmed it. Further investigation failed to reveal the cause of the hypoglycaemia and in some cases because of a "flat" glucose tolerance
curve organic hyperinsulinism was suspected. In one case total pancreatectomy was performed but thorough macroscopical and histological investigation failed to reveal a tumour or hyperplasia, and the patient subsequently suffered from diabetes. In August 1958, I admitted an African female patient, of 26 years, to the ward in coma. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/32024 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:01.081Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/32024 Post-alcoholic hypoglycaemia: a clinical and pathological study Naeme, Peter Brereton Alcoholism Complications For a number of years a history of sudden onset of coma, followed later by death, was noted amongst Africans at King Edward VIII hospital, Durban. Necropsy, where performed, revealed no cause in many of these patients. In 1957 after cerebrospinal fluid had been examined in some of the cases it was seen that the only abnormality present was a low cerebrospinal sugar. Hypoglycaemia was suspected and blood sugar estimation confirmed it. Further investigation failed to reveal the cause of the hypoglycaemia and in some cases because of a "flat" glucose tolerance curve organic hyperinsulinism was suspected. In one case total pancreatectomy was performed but thorough macroscopical and histological investigation failed to reveal a tumour or hyperplasia, and the patient subsequently suffered from diabetes. In August 1958, I admitted an African female patient, of 26 years, to the ward in coma. 2020-06-02T11:17:13Z 2020-06-02T11:17:13Z 1965 2020-04-09T10:28:32Z Doctoral Thesis Doctoral https://hdl.handle.net/11427/32024 eng application/pdf Department of Medicine Faculty of Health Sciences |
| spellingShingle | Alcoholism Complications Naeme, Peter Brereton Post-alcoholic hypoglycaemia: a clinical and pathological study |
| thesis_degree_str | Doctoral |
| title | Post-alcoholic hypoglycaemia: a clinical and pathological study |
| title_full | Post-alcoholic hypoglycaemia: a clinical and pathological study |
| title_fullStr | Post-alcoholic hypoglycaemia: a clinical and pathological study |
| title_full_unstemmed | Post-alcoholic hypoglycaemia: a clinical and pathological study |
| title_short | Post-alcoholic hypoglycaemia: a clinical and pathological study |
| title_sort | post alcoholic hypoglycaemia a clinical and pathological study |
| topic | Alcoholism Complications |
| url | https://hdl.handle.net/11427/32024 |
| work_keys_str_mv | AT naemepeterbrereton postalcoholichypoglycaemiaaclinicalandpathologicalstudy |