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Determination of Rifapentine and 25-O-desacetyl Rifapentine from 100 µl human breastmilk by LC-MS/MS using protein precipitation and solid phase extraction

There is currently no information available on the transfer of the second-line anti-TB drug, rifapentine and its metabolite, into breastmilk. The subsequent implications to the breastfed infant, as well as consequences of long-term exposure to potentially sub-therapeutic drug levels with regards to...

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Bibliographic Details
Main Author: Mkhize, Buyisile
Other Authors: Wiesner, Lubbe
Format: Thesis
Language:English
Published: Department of Medicine 2020
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