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The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis
Includes bibliographical references (leaves 115-128).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Human Biology
2014
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| _version_ | 1867613266518212608 |
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| access_status_str | Open Access |
| author | Hsu, Nai-Jen |
| author2 | Lang, Dirk M |
| author_browse | Hsu, Nai-Jen Lang, Dirk M |
| author_facet | Lang, Dirk M Hsu, Nai-Jen |
| author_sort | Hsu, Nai-Jen |
| collection | Thesis |
| description | Includes bibliographical references (leaves 115-128). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3249 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:25.185Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Human Biology |
| publisherStr | Department of Human Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3249 The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis Hsu, Nai-Jen Lang, Dirk M Human Biology Includes bibliographical references (leaves 115-128). Generally, the factors contributing to success or failure of axon regeneration lie in the intrinsic properties of the injured neurons, as well as the surrounding microenvironment of the transected axon. Mammalian neurons may lack the intrinsic ability to survive after trauma, or to re-express genes required for axonal regrowth. Moreover, several proteins inhibitory to neurite growth, such as Tenascin-R (TN-R) and Nogo-A, have been identified in mammals. These proteins are associated with oligodendrocytes and myelin and are considered major inhibitory components of the CNS environment. 2014-07-28T18:16:48Z 2014-07-28T18:16:48Z 2007 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3249 eng application/pdf Department of Human Biology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Human Biology Hsu, Nai-Jen The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis |
| thesis_degree_str | Doctoral |
| title | The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis |
| title_full | The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis |
| title_fullStr | The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis |
| title_full_unstemmed | The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis |
| title_short | The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis |
| title_sort | expression and functional analysis of neurite outgrowth inhibitors in the nervous system of xenopus laevis |
| topic | Human Biology |
| url | http://hdl.handle.net/11427/3249 |
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