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Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant Acinetobacter baumannii infections
Includes bibliographical references (leaves 42-47).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Division of Clinical Pharmacology
2014
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| _version_ | 1867613235080855552 |
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| access_status_str | Open Access |
| author | Gounden, Ronald |
| author2 | Maartens, Gary |
| author_browse | Gounden, Ronald Maartens, Gary |
| author_facet | Maartens, Gary Gounden, Ronald |
| author_sort | Gounden, Ronald |
| collection | Thesis |
| description | Includes bibliographical references (leaves 42-47). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3282 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:54.720Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Division of Clinical Pharmacology |
| publisherStr | Division of Clinical Pharmacology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3282 Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant Acinetobacter baumannii infections Gounden, Ronald Maartens, Gary Cohen, Karen Clinical Pharmacology Includes bibliographical references (leaves 42-47). Background: Nosocomial infections due to multi-drug resistant Acinetobacter baumannii are often treated with colistin, but there are few data comparing its safety and effectiveness with other antimicrobials, particularly the aminoglycosides. Metbods: A retrospective cohort study of patients treated with colistin or tobramycin for A. baumannii infections in intensive care units (ICUs) at Groote Schuur hospital was performed. Colistin was used for A baumannii isolates which were resistant to all other available antimicrobials. Tobramycin was used when the organism was susceptible to this antimicrobial. We assessed and compared ICU mortality, nephrotoxicity and time to the first negative culture in the colistin and tobramycin groups. 2014-07-28T18:18:57Z 2014-07-28T18:18:57Z 2009 Master Thesis Masters MMed http://hdl.handle.net/11427/3282 eng application/pdf Division of Clinical Pharmacology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Clinical Pharmacology Gounden, Ronald Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant Acinetobacter baumannii infections |
| thesis_degree_str | Master's |
| title | Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant Acinetobacter baumannii infections |
| title_full | Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant Acinetobacter baumannii infections |
| title_fullStr | Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant Acinetobacter baumannii infections |
| title_full_unstemmed | Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant Acinetobacter baumannii infections |
| title_short | Safety and effectiveness of colistin compared with tobramycin for multi-drug resistant Acinetobacter baumannii infections |
| title_sort | safety and effectiveness of colistin compared with tobramycin for multi drug resistant acinetobacter baumannii infections |
| topic | Clinical Pharmacology |
| url | http://hdl.handle.net/11427/3282 |
| work_keys_str_mv | AT goundenronald safetyandeffectivenessofcolistincomparedwithtobramycinformultidrugresistantacinetobacterbaumanniiinfections |