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The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review
Background: Childhood tuberculosis (TB) is a common disease worldwide, with an increased propensity for severe, disseminated disease in settings with a high burden of concomitant HIV infection. Ultrasound is commonly used in diagnosing abdominal TB, however the indications for its use are unclear an...
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| Format: | Thesis |
| Language: | English |
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Division of Radiology
2021
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| _version_ | 1867613236373749760 |
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| access_status_str | Open Access |
| author | Sood, Vishesh |
| author2 | Kilborn, Tracy |
| author_browse | Kilborn, Tracy Sood, Vishesh |
| author_facet | Kilborn, Tracy Sood, Vishesh |
| author_sort | Sood, Vishesh |
| collection | Thesis |
| description | Background: Childhood tuberculosis (TB) is a common disease worldwide, with an increased propensity for severe, disseminated disease in settings with a high burden of concomitant HIV infection. Ultrasound is commonly used in diagnosing abdominal TB, however the indications for its use are unclear and often vary amongst clinicians. Objective: In this study, we describe the findings of ultrasound examinations performed for suspected abdominal TB at a tertiary children's hospital and examine the variability in reporting patterns amongst radiologists performing these imaging investigations. Materials and methods: Ultrasound studies performed for “suspected abdominal TB” between 01 January 2013 – 31 December 2018 were reviewed. In studies reported as suggestive of abdominal TB, evidence of microbiologically confirmed disease was sought. Subsequently, a selection of images from these studies were independently reviewed by three paediatric radiologists to determine their level of agreement when interpreting imaging findings. Results: During the study period 1093 studies were performed for suspected abdominal TB, of which 166 (15%) had abnormal features suggestive of TB. Forty-seven percent of these patients (78/166) had microbiologically confirmed disease. The commonest reported features were lymphadenopathy, 77% (128/166) and splenic microabscesses, 55% (92/166) for which substantial inter-reader agreement was documented, Fleiss' kappa = 0.64 and 0.66 respectively. There was moderate inter-reader agreement in the diagnosis of abdominal TB among radiologists (Fleiss' kappa=0.47). Conclusion: Caution is advised when basing clinical decisions on ultrasound studies performed for suspected abdominal TB, as imaging features are non-specific and there is considerable variability in interpretation of studies among reporting radiologists. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/33037 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:56.154Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Division of Radiology |
| publisherStr | Division of Radiology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/33037 The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review Sood, Vishesh Kilborn, Tracy Eley, Brian Radiodiagnosis Background: Childhood tuberculosis (TB) is a common disease worldwide, with an increased propensity for severe, disseminated disease in settings with a high burden of concomitant HIV infection. Ultrasound is commonly used in diagnosing abdominal TB, however the indications for its use are unclear and often vary amongst clinicians. Objective: In this study, we describe the findings of ultrasound examinations performed for suspected abdominal TB at a tertiary children's hospital and examine the variability in reporting patterns amongst radiologists performing these imaging investigations. Materials and methods: Ultrasound studies performed for “suspected abdominal TB” between 01 January 2013 – 31 December 2018 were reviewed. In studies reported as suggestive of abdominal TB, evidence of microbiologically confirmed disease was sought. Subsequently, a selection of images from these studies were independently reviewed by three paediatric radiologists to determine their level of agreement when interpreting imaging findings. Results: During the study period 1093 studies were performed for suspected abdominal TB, of which 166 (15%) had abnormal features suggestive of TB. Forty-seven percent of these patients (78/166) had microbiologically confirmed disease. The commonest reported features were lymphadenopathy, 77% (128/166) and splenic microabscesses, 55% (92/166) for which substantial inter-reader agreement was documented, Fleiss' kappa = 0.64 and 0.66 respectively. There was moderate inter-reader agreement in the diagnosis of abdominal TB among radiologists (Fleiss' kappa=0.47). Conclusion: Caution is advised when basing clinical decisions on ultrasound studies performed for suspected abdominal TB, as imaging features are non-specific and there is considerable variability in interpretation of studies among reporting radiologists. 2021-03-01T18:46:21Z 2021-03-01T18:46:21Z 2020 2021-03-01T12:24:15Z Master Thesis Masters MMed http://hdl.handle.net/11427/33037 eng application/pdf Division of Radiology Faculty of Health Sciences |
| spellingShingle | Radiodiagnosis Sood, Vishesh The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review |
| thesis_degree_str | Master's |
| title | The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review |
| title_full | The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review |
| title_fullStr | The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review |
| title_full_unstemmed | The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review |
| title_short | The utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis: a single centre review |
| title_sort | utility of abdominal ultrasound in the diagnosis of paediatric abdominal tuberculosis a single centre review |
| topic | Radiodiagnosis |
| url | http://hdl.handle.net/11427/33037 |
| work_keys_str_mv | AT soodvishesh theutilityofabdominalultrasoundinthediagnosisofpaediatricabdominaltuberculosisasinglecentrereview AT soodvishesh utilityofabdominalultrasoundinthediagnosisofpaediatricabdominaltuberculosisasinglecentrereview |