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Polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia (Type III hyperlipidaemia)
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Medicine
2014
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| _version_ | 1867614233266487296 |
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| access_status_str | Open Access |
| author | Blom, Dirk Jacobus |
| author2 | Marais, David |
| author_browse | Blom, Dirk Jacobus Marais, David |
| author_facet | Marais, David Blom, Dirk Jacobus |
| author_sort | Blom, Dirk Jacobus |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3365 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:48:47.221Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3365 Polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia (Type III hyperlipidaemia) Blom, Dirk Jacobus Marais, David Includes bibliographical references. Accurate phenotypic diagnosis of this disorder has generally relied on the quantitative analysis of centrifugally isolated VLDL. Analysis of VLDL chemical composition is not widely available due to the expense of acquiring ultracentrifuges and the highly-skilled staff necessary to perform the analyses. Genotypic diagnosis is somewhat more widely available, especially testing for the E2/E2 genotype which is the commonest underlying genotype in dysbetalipoproteinaemia. Testing for the rarer autosomal mutations of ApoE is restricted to a small number of centres only. In this study I will review dysbetalipoproteinaemia briefly and then describe and evaluate GGE as a new diagnostic technique for this disorder. 2014-07-29T09:02:47Z 2014-07-29T09:02:47Z 2001 Master Thesis Masters MMed http://hdl.handle.net/11427/3365 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Blom, Dirk Jacobus Polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia (Type III hyperlipidaemia) |
| thesis_degree_str | Master's |
| title | Polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia (Type III hyperlipidaemia) |
| title_full | Polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia (Type III hyperlipidaemia) |
| title_fullStr | Polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia (Type III hyperlipidaemia) |
| title_full_unstemmed | Polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia (Type III hyperlipidaemia) |
| title_short | Polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia (Type III hyperlipidaemia) |
| title_sort | polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia type iii hyperlipidaemia |
| url | http://hdl.handle.net/11427/3365 |
| work_keys_str_mv | AT blomdirkjacobus polyacrylamidegradientgelelectrophoresisforthediagnosisofdysbetalipoproteinaemiatypeiiihyperlipidaemia |