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The regulation of matrix metalloproteinase (MMP) secretion in human vascular cells exposed to extracellular and wound matrices

Includes bibliographical references.

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Bibliographic Details
Main Author: Bracher, Mona
Other Authors: Davies, Neil
Format: Thesis
Language:English
Published: Department of Medicine 2014
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access_status_str Open Access
author Bracher, Mona
author2 Davies, Neil
author_browse Bracher, Mona
Davies, Neil
author_facet Davies, Neil
Bracher, Mona
author_sort Bracher, Mona
collection Thesis
description Includes bibliographical references.
format Thesis
id oai:open.uct.ac.za:11427/3368
institution University of Cape Town (South Africa)
language eng
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2014
publishDateRange 2014
publishDateSort 2014
publisher Department of Medicine
publisherStr Department of Medicine
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/3368 The regulation of matrix metalloproteinase (MMP) secretion in human vascular cells exposed to extracellular and wound matrices Bracher, Mona Davies, Neil Zilla, Peter Includes bibliographical references. Proteolytic degradation is a central feature of the cellular remodelling in wounds during healing. The regulation of matrix metalloproteinases (a key superfamily of proteases involved in the above process) by wound healing components is an area of ongoing investigation. However, a systematic study of the exposure of the human derived vascular cells - endothelial cells, fibroblasts, smooth muscle cells and macrophages - to well defined ECM (collagen type I, III and IV and laminin) and wound healing matrix proteins (fibrin and plasma fibronectin) has not yet beeen carried out. 2014-07-29T09:02:51Z 2014-07-29T09:02:51Z 2002 Thesis MSc Thesis http://hdl.handle.net/11427/3368 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town
spellingShingle Bracher, Mona
The regulation of matrix metalloproteinase (MMP) secretion in human vascular cells exposed to extracellular and wound matrices
thesis_degree_str Master's
title The regulation of matrix metalloproteinase (MMP) secretion in human vascular cells exposed to extracellular and wound matrices
title_full The regulation of matrix metalloproteinase (MMP) secretion in human vascular cells exposed to extracellular and wound matrices
title_fullStr The regulation of matrix metalloproteinase (MMP) secretion in human vascular cells exposed to extracellular and wound matrices
title_full_unstemmed The regulation of matrix metalloproteinase (MMP) secretion in human vascular cells exposed to extracellular and wound matrices
title_short The regulation of matrix metalloproteinase (MMP) secretion in human vascular cells exposed to extracellular and wound matrices
title_sort regulation of matrix metalloproteinase mmp secretion in human vascular cells exposed to extracellular and wound matrices
url http://hdl.handle.net/11427/3368
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