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The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Medicine
2014
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| _version_ | 1867613212211412992 |
|---|---|
| access_status_str | Open Access |
| author | Matsabisa, Motlalepula Gilbert |
| author2 | Folb, Peter I |
| author_browse | Folb, Peter I Matsabisa, Motlalepula Gilbert |
| author_facet | Folb, Peter I Matsabisa, Motlalepula Gilbert |
| author_sort | Matsabisa, Motlalepula Gilbert |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3427 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:33.381Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3427 The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro Matsabisa, Motlalepula Gilbert Folb, Peter I Smith, Peter J Campbell, William E Medicine Includes bibliographical references. Two plants, Dicoma anomala [Sond.]; a member of the Asteraceae and Sclerocarya birrea [(A. Rich) Hoechst. subspecies caffra (Sond.) Kokwaro], a member of the Anarcadiaceae families, are used widely in Africa for a variety of traditional treatments. In this thesis it has been shown that these plants possess in vitro pharmacological activities against the malaria parasite. The extracts of D. anomala are active in vitro against Plasmodium falciparum and those of S. birrea selectively enhance the in vitro accumulation of chloroquine in resistant strains of Plasmodium falciparum. 2014-07-29T09:07:18Z 2014-07-29T09:07:18Z 2001 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3427 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Matsabisa, Motlalepula Gilbert The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro |
| thesis_degree_str | Doctoral |
| title | The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro |
| title_full | The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro |
| title_fullStr | The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro |
| title_full_unstemmed | The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro |
| title_short | The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro |
| title_sort | antimalarial activity of dicoma anomala and the chloroquine resistance reversing effects of sclerocarya birrea on plasmodium falciparum in vitro |
| topic | Medicine |
| url | http://hdl.handle.net/11427/3427 |
| work_keys_str_mv | AT matsabisamotlalepulagilbert theantimalarialactivityofdicomaanomalaandthechloroquineresistancereversingeffectsofsclerocaryabirreaonplasmodiumfalciparuminvitro AT matsabisamotlalepulagilbert antimalarialactivityofdicomaanomalaandthechloroquineresistancereversingeffectsofsclerocaryabirreaonplasmodiumfalciparuminvitro |