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The role of melatonin in peripartum cardiomyopathy

Includes abstract.

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Bibliographic Details
Main Author: Nicholson, Lauren
Other Authors: Lecour, Sandrine
Format: Thesis
Language:English
Published: Department of Medicine 2014
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access_status_str Open Access
author Nicholson, Lauren
author2 Lecour, Sandrine
author_browse Lecour, Sandrine
Nicholson, Lauren
author_facet Lecour, Sandrine
Nicholson, Lauren
author_sort Nicholson, Lauren
collection Thesis
description Includes abstract.
format Thesis
id oai:open.uct.ac.za:11427/3444
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:31:45.395Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2014
publishDateRange 2014
publishDateSort 2014
publisher Department of Medicine
publisherStr Department of Medicine
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/3444 The role of melatonin in peripartum cardiomyopathy Nicholson, Lauren Lecour, Sandrine Sliwa, Karen Medicine Includes abstract. Includes bibliographical references. Peripartum cardiomyopathy (PPCM) is a heart disease of unknown aetiology emerging in previously healthy women towards the end of pregnancy or first postpartum months. Previous studies have suggested that oxidative stress contributes to the pathogenesis of PPCM. Melatonin is a powerful endogenous antioxidant that can limit the damaging effect of oxidative stress. Melatonin levels are known to be altered in sleep disruption, depression and other cardiac diseases. The aim of this study was to determine if melatonin levels are disrupted in women with PPCM compared to healthy patients. We hypothesised that sleep disruption and depression may contribute to a disruption in their melatonin levels. 2014-07-29T09:08:55Z 2014-07-29T09:08:55Z 2013 Master Thesis Masters MSc http://hdl.handle.net/11427/3444 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town
spellingShingle Medicine
Nicholson, Lauren
The role of melatonin in peripartum cardiomyopathy
thesis_degree_str Master's
title The role of melatonin in peripartum cardiomyopathy
title_full The role of melatonin in peripartum cardiomyopathy
title_fullStr The role of melatonin in peripartum cardiomyopathy
title_full_unstemmed The role of melatonin in peripartum cardiomyopathy
title_short The role of melatonin in peripartum cardiomyopathy
title_sort role of melatonin in peripartum cardiomyopathy
topic Medicine
url http://hdl.handle.net/11427/3444
work_keys_str_mv AT nicholsonlauren theroleofmelatonininperipartumcardiomyopathy
AT nicholsonlauren roleofmelatonininperipartumcardiomyopathy