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Includes abstract.
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| Format: | Thesis |
| Language: | English |
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Department of Medicine
2014
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| _version_ | 1867613201817927680 |
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| access_status_str | Open Access |
| author | Okpechi, Ikechi Gareth |
| author2 | Meissner, P |
| author_browse | Meissner, P Okpechi, Ikechi Gareth |
| author_facet | Meissner, P Okpechi, Ikechi Gareth |
| author_sort | Okpechi, Ikechi Gareth |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3446 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:21.936Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3446 Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans Okpechi, Ikechi Gareth Meissner, P Rayner, B L Ramesar, R Pascoe, M D Medicine Includes abstract. Includes bibliographical references (leaves 226-256). Obesity is a worldwide problem and is a factor in the pathogenesis of the metabolic syndrome and kidney disease through the development of obesity-related hypertension and neurohormonal mechanisms that include the action of leptin. As there appear to be no focussed studies that have looked at the association of the LEP gene with kidney disease phenotypes or cardiovascular disease markers like hypertension, the metabolic syndrome and obesity, and especially so in native black Africans, this study sought to establish an association between the obesity gene (LEP) and kidney disease phenotypes (independent of diabetes and hypertension) in a homogenous black African population. 2014-07-29T09:09:23Z 2014-07-29T09:09:23Z 2008 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3446 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Okpechi, Ikechi Gareth Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans |
| thesis_degree_str | Doctoral |
| title | Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans |
| title_full | Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans |
| title_fullStr | Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans |
| title_full_unstemmed | Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans |
| title_short | Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans |
| title_sort | metabolic syndrome the leptin gene and kidney disease in non diabetic black south africans |
| topic | Medicine |
| url | http://hdl.handle.net/11427/3446 |
| work_keys_str_mv | AT okpechiikechigareth metabolicsyndrometheleptingeneandkidneydiseaseinnondiabeticblacksouthafricans |