Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease
Includes bibliographical references (leaves 113-124).
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Medicine
2014
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613219406741504 |
|---|---|
| access_status_str | Open Access |
| author | Scholefield, Janine |
| author2 | Greenberg, Jacquie |
| author_browse | Greenberg, Jacquie Scholefield, Janine |
| author_facet | Greenberg, Jacquie Scholefield, Janine |
| author_sort | Scholefield, Janine |
| collection | Thesis |
| description | Includes bibliographical references (leaves 113-124). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3460 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:39.476Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3460 Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease Scholefield, Janine Greenberg, Jacquie Goliath, Rene Medicine Includes bibliographical references (leaves 113-124). The primary aim of this study was to investigate the origins of the HD mutation in South Africa (SA) by constructing a single nucleotide polymorphism (SNP) haplotype around the IT15 gene and to determine how many haplotypes there are in SA. Haplotypes were created by genotyping 6 SNPs in a total of 15 HD families. These families were comprised of seven Caucasian, 6 Mixed Ancestry and two Black African families. 2014-07-29T09:10:20Z 2014-07-29T09:10:20Z 2005 Master Thesis Masters MSc http://hdl.handle.net/11427/3460 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Scholefield, Janine Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease |
| thesis_degree_str | Master's |
| title | Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease |
| title_full | Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease |
| title_fullStr | Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease |
| title_full_unstemmed | Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease |
| title_short | Detailed investigation of the unstable (CAG) repeat and the immediate surrounding region of the IT15 gene in some South African families with Huntington disease |
| title_sort | detailed investigation of the unstable cag repeat and the immediate surrounding region of the it15 gene in some south african families with huntington disease |
| topic | Medicine |
| url | http://hdl.handle.net/11427/3460 |
| work_keys_str_mv | AT scholefieldjanine detailedinvestigationoftheunstablecagrepeatandtheimmediatesurroundingregionoftheit15geneinsomesouthafricanfamilieswithhuntingtondisease |