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Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country

Objective: To evaluate the impact of small for gestational age on outcomes of very low birth weight infants at Groote Schuur Hospital, Cape Town, South Africa. Study design: Data was obtained from Vermont Oxford Network Groote Schuur Hospital database from 2012 to 2018. Fenton growth charts were use...

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Main Author: Mangiza, Marcia
Other Authors: Tooke, Lloyd
Format: Thesis
Language:English
Published: Department of Paediatrics and Child Health 2022
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access_status_str Open Access
author Mangiza, Marcia
author2 Tooke, Lloyd
author_browse Mangiza, Marcia
Tooke, Lloyd
author_facet Tooke, Lloyd
Mangiza, Marcia
author_sort Mangiza, Marcia
collection Thesis
description Objective: To evaluate the impact of small for gestational age on outcomes of very low birth weight infants at Groote Schuur Hospital, Cape Town, South Africa. Study design: Data was obtained from Vermont Oxford Network Groote Schuur Hospital database from 2012 to 2018. Fenton growth charts were used to define small for gestational age as birth weight < 10th centile for gestational age. Results: Mortality (28.9% vs 18.5%, adjusted risk ratio (aRR) 2.1, 95% confidence interval (CI) 1.6-2.7), bronchopulmonary dysplasia (14% vs 4.5%, aRR 3.7, 95% CI 2.3-6.1) and late onset sepsis (16.7% vs 9.6%, aRR 2.3, 95% CI 1.6-3.3) were higher in the small for gestational age than in the non-small for gestational age group. Conclusion: Small for gestational age infants have a higher risk of mortality and morbidity among very low birth weight infants at Groote Schuur Hospital. This may be useful for counseling and perinatal management.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:34:27.383Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher Department of Paediatrics and Child Health
publisherStr Department of Paediatrics and Child Health
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/35939 Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country Mangiza, Marcia Tooke, Lloyd Rhoda, Natasha Raygaan Neonatology Objective: To evaluate the impact of small for gestational age on outcomes of very low birth weight infants at Groote Schuur Hospital, Cape Town, South Africa. Study design: Data was obtained from Vermont Oxford Network Groote Schuur Hospital database from 2012 to 2018. Fenton growth charts were used to define small for gestational age as birth weight < 10th centile for gestational age. Results: Mortality (28.9% vs 18.5%, adjusted risk ratio (aRR) 2.1, 95% confidence interval (CI) 1.6-2.7), bronchopulmonary dysplasia (14% vs 4.5%, aRR 3.7, 95% CI 2.3-6.1) and late onset sepsis (16.7% vs 9.6%, aRR 2.3, 95% CI 1.6-3.3) were higher in the small for gestational age than in the non-small for gestational age group. Conclusion: Small for gestational age infants have a higher risk of mortality and morbidity among very low birth weight infants at Groote Schuur Hospital. This may be useful for counseling and perinatal management. 2022-03-06T15:58:25Z 2022-03-06T15:58:25Z 2021 2022-03-06T07:13:33Z Master Thesis Masters MPhil http://hdl.handle.net/11427/35939 eng application/pdf Department of Paediatrics and Child Health Faculty of Health Sciences
spellingShingle Neonatology
Mangiza, Marcia
Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country
thesis_degree_str Master's
title Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country
title_full Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country
title_fullStr Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country
title_full_unstemmed Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country
title_short Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country
title_sort morbidity and mortality in small for gestational age very low birth weight infants in a middle income country
topic Neonatology
url http://hdl.handle.net/11427/35939
work_keys_str_mv AT mangizamarcia morbidityandmortalityinsmallforgestationalageverylowbirthweightinfantsinamiddleincomecountry