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Investigation of the potential of Spleen Tyrosine Kinase (SYK) as a target for host-directed therapy during mycobacterial infection in macrophages

Tuberculosis (TB) is a communicable disease caused by a single infectious agent, Mycobacterium tuberculosis (Mtb). TB affects mostly the lungs and despite treatment being available, it still causes long term functional disability due to collateral tissue damage. The TBburden is exacerbated by the le...

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Bibliographic Details
Main Author: Mohapi, Sephekana Samuel
Other Authors: Marakalala, Mohlopheni Jackson
Format: Thesis
Language:English
Published: Department of Clinical Laboratory Sciences 2022
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