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Role of extracellular environment in mechanical properties of human cardiac fibroblasts and myofibroblasts

Acute MI results in adverse remodelling of the myocardium, eventually leading to contractile dysfunction and chronic heart failure. Collectively, the formation of fibrotic scar tissue in the left ventricle inhibits its contractile function and leads to a cardiac output loss. Cardiac fibroblast and m...

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Bibliographic Details
Main Author: Haasbroek, Pieter Daniël
Other Authors: Franz, Thomas
Format: Thesis
Language:English
Published: Department of Human Biology 2022
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