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Synthesis and biological evaluation of auristatin-F recombinant antibody-drug conjugates for cancer therapy

This study serves as a contribution to the emerging field of antibody-drug conjugate (ADC) therapeutics, in which novel ADCs were generated and biologically evaluated for therapeutic potential and specificity towards cancer cells. SNAP-tag site-directed conjugation was employed in order to overcome...

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Bibliographic Details
Main Author: Huysamen, Allan Martin
Other Authors: Hunter, Roger
Format: Thesis
Language:English
Published: Department of Chemistry 2023
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