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A demographic review of stage of presentation and survival rates of head and neck cancer patients in the Western Cape, South Africa

Most literature reports significantly poorer access to healthcare, more advanced cancers, and worse survival in rural and remote populations. This study investigates if significant disparities exist with regard to stage at presentation and overall survival of patients with head and neck cancer (HNC)...

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Main Author: Honnet, Simon
Other Authors: Fagan, Johannes
Format: Thesis
Language:English
Published: Division of Otolaryngology 2023
Subjects:
Otolaryngology
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access_status_str Open Access
author Honnet, Simon
author2 Fagan, Johannes
author_browse Fagan, Johannes
Honnet, Simon
author_facet Fagan, Johannes
Honnet, Simon
author_sort Honnet, Simon
collection Thesis
description Most literature reports significantly poorer access to healthcare, more advanced cancers, and worse survival in rural and remote populations. This study investigates if significant disparities exist with regard to stage at presentation and overall survival of patients with head and neck cancer (HNC) between geographical areas within the Western Cape Province in South Africa. A retrospective chart review was conducted on all patients managed with both curative and palliative intent through the Combined ENT/Head and Neck Oncology clinic at Groote Schuur Hospital in the five-year period from January 2010 to December 2014. Ethics approval was granted by the University of Cape Town Human Research Ethics Committee (HREC, 351-2017). Although we observed no significant difference in TNM clinical stages or overall survival between metropolitan and remote patients, there were statistically and clinically significant differences in terms of both stages of HNC and survival between some individual metropolitan and remote areas. The remote area of Eden had a median overall survival of more than 6 months less than that of the Southern subdistrict of the City of Cape Town. These discrepancies in HNC stages and survival are likely multifactorial, involving socioeconomic and demographic factors in addition to geographic factors.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:32:03.909Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher Division of Otolaryngology
publisherStr Division of Otolaryngology
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/37284 A demographic review of stage of presentation and survival rates of head and neck cancer patients in the Western Cape, South Africa Honnet, Simon Fagan, Johannes Otolaryngology Most literature reports significantly poorer access to healthcare, more advanced cancers, and worse survival in rural and remote populations. This study investigates if significant disparities exist with regard to stage at presentation and overall survival of patients with head and neck cancer (HNC) between geographical areas within the Western Cape Province in South Africa. A retrospective chart review was conducted on all patients managed with both curative and palliative intent through the Combined ENT/Head and Neck Oncology clinic at Groote Schuur Hospital in the five-year period from January 2010 to December 2014. Ethics approval was granted by the University of Cape Town Human Research Ethics Committee (HREC, 351-2017). Although we observed no significant difference in TNM clinical stages or overall survival between metropolitan and remote patients, there were statistically and clinically significant differences in terms of both stages of HNC and survival between some individual metropolitan and remote areas. The remote area of Eden had a median overall survival of more than 6 months less than that of the Southern subdistrict of the City of Cape Town. These discrepancies in HNC stages and survival are likely multifactorial, involving socioeconomic and demographic factors in addition to geographic factors. 2023-03-07T07:37:54Z 2023-03-07T07:37:54Z 2022 2023-02-20T12:56:08Z Master Thesis Masters MMed http://hdl.handle.net/11427/37284 eng application/pdf Division of Otolaryngology Faculty of Health Sciences
spellingShingle Otolaryngology
Honnet, Simon
A demographic review of stage of presentation and survival rates of head and neck cancer patients in the Western Cape, South Africa
thesis_degree_str Master's
title A demographic review of stage of presentation and survival rates of head and neck cancer patients in the Western Cape, South Africa
title_full A demographic review of stage of presentation and survival rates of head and neck cancer patients in the Western Cape, South Africa
title_fullStr A demographic review of stage of presentation and survival rates of head and neck cancer patients in the Western Cape, South Africa
title_full_unstemmed A demographic review of stage of presentation and survival rates of head and neck cancer patients in the Western Cape, South Africa
title_short A demographic review of stage of presentation and survival rates of head and neck cancer patients in the Western Cape, South Africa
title_sort demographic review of stage of presentation and survival rates of head and neck cancer patients in the western cape south africa
topic Otolaryngology
url http://hdl.handle.net/11427/37284
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AT honnetsimon demographicreviewofstageofpresentationandsurvivalratesofheadandneckcancerpatientsinthewesterncapesouthafrica

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