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Design of Selective Plasmodium falciparum Kinase Inhibitors using Computer-Aided Drug Discovery
The discovery of antimalarials with novel mechanisms of action able to circumvent resistance is crucial. This target-based drug discovery campaign is based on the following Plasmodium kinases: Plasmodium falciparum phosphatidylinositol 4-kinase (PfPI4K) and Plasmodium falciparum cyclic guanosine mon...
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| Format: | Thesis |
| Language: | English |
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Department of Chemistry
2023
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