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Pharmacogenetics of Tenofovir (Alafenamide or Disoproxil Fumarate Prodrug) Renal Toxicity in HIV positive Black Southern Africans
Background: Among individuals treated for HIV-1 infection, renal toxicity is more likely with tenofovir disoproxil fumarate (TDF) than with tenofovir alafenamide (TAF). Limited previous studies suggest potential genetic associations with TDF-associated renal toxicity. We hypothesized that polymorphi...
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| Format: | Thesis |
| Language: | English |
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Department of Medicine
2023
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