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Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients
Introduction: Below knee amputation is the safest treatment for aggressive benign and malignant bone tumours of the distal tibia yielding good oncological and functional results. However, in selected patients where limb salvage is feasible and amputation unacceptable to the patient, limb salvage usi...
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| Format: | Thesis |
| Language: | English |
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Division of General Surgery
2023
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| _version_ | 1867614464187039744 |
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| access_status_str | Open Access |
| author | Mugla, Walid |
| author2 | Hilton, Thomas |
| author_browse | Hilton, Thomas Mugla, Walid |
| author_facet | Hilton, Thomas Mugla, Walid |
| author_sort | Mugla, Walid |
| collection | Thesis |
| description | Introduction: Below knee amputation is the safest treatment for aggressive benign and malignant bone tumours of the distal tibia yielding good oncological and functional results. However, in selected patients where limb salvage is feasible and amputation unacceptable to the patient, limb salvage using a distal tibial replacement (DTR) can be considered. This study aims to present the oncological and functional results of the use of this treatment method in our unit. Patients & Methods: A retrospective folder review was performed for all 10 patients who received a modular distal tibial replacement between 01/01/2005 and 31/01/2019 for a primary bone tumour either benign aggressive or malignant. Six were female and the mean age was 31 (1275) years. There were five patients with giant cell tumour of bone, four with osteosarcoma and one with a low-grade chondrosarcoma. The patients with osteosarcoma had neo-adjuvant chemotherapy before surgery. Function was assessed by the Musculoskeletal Tumor Society (MSTS) score. Results: There were six females and four males, with a mean age of 31 (12-75) years. Two patients had local recurrence treated with a BKA and one other patient died of metastases three years postoperatively. At a mean follow-up of three years, the remaining eight patients had a mean MSTS score of 83% (67–93%). There were no radiological signs of loosening, and no revision surgeries. Conclusion: Endoprosthetic replacement of the distal tibia for primary bone tumours can be a safe treatment option in very selected cases. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/37854 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:52:27.444Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Division of General Surgery |
| publisherStr | Division of General Surgery |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/37854 Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients Mugla, Walid Hilton, Thomas distal tibia endoprosthetic replacement osteosarcoma giant cell tumour limb salvage amputation Introduction: Below knee amputation is the safest treatment for aggressive benign and malignant bone tumours of the distal tibia yielding good oncological and functional results. However, in selected patients where limb salvage is feasible and amputation unacceptable to the patient, limb salvage using a distal tibial replacement (DTR) can be considered. This study aims to present the oncological and functional results of the use of this treatment method in our unit. Patients & Methods: A retrospective folder review was performed for all 10 patients who received a modular distal tibial replacement between 01/01/2005 and 31/01/2019 for a primary bone tumour either benign aggressive or malignant. Six were female and the mean age was 31 (1275) years. There were five patients with giant cell tumour of bone, four with osteosarcoma and one with a low-grade chondrosarcoma. The patients with osteosarcoma had neo-adjuvant chemotherapy before surgery. Function was assessed by the Musculoskeletal Tumor Society (MSTS) score. Results: There were six females and four males, with a mean age of 31 (12-75) years. Two patients had local recurrence treated with a BKA and one other patient died of metastases three years postoperatively. At a mean follow-up of three years, the remaining eight patients had a mean MSTS score of 83% (67–93%). There were no radiological signs of loosening, and no revision surgeries. Conclusion: Endoprosthetic replacement of the distal tibia for primary bone tumours can be a safe treatment option in very selected cases. 2023-04-28T13:41:43Z 2023-04-28T13:41:43Z 2022 2023-04-28T13:41:25Z Master Thesis Masters MMed http://hdl.handle.net/11427/37854 eng application/pdf Division of General Surgery Faculty of Health Sciences |
| spellingShingle | distal tibia endoprosthetic replacement osteosarcoma giant cell tumour limb salvage amputation Mugla, Walid Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients |
| thesis_degree_str | Master's |
| title | Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients |
| title_full | Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients |
| title_fullStr | Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients |
| title_full_unstemmed | Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients |
| title_short | Modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients |
| title_sort | modular prosthetic reconstruction for primary bone tumours of the distal tibia in ten patients |
| topic | distal tibia endoprosthetic replacement osteosarcoma giant cell tumour limb salvage amputation |
| url | http://hdl.handle.net/11427/37854 |
| work_keys_str_mv | AT muglawalid modularprostheticreconstructionforprimarybonetumoursofthedistaltibiaintenpatients |