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In silico redesign and de novo design of anti-MUC1 monoclonal antibodies
Mucin 1 (MUC1) is a cellular membrane-tethered protein which is abnormally glycosylated and overexpressed in several epithelial cancers. This abnormal glycosylation is hypothesized to participate in the hyper-activation of signaling pathways which promote tumor growth and provides a suitable target...
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| Format: | Thesis |
| Language: | Eng |
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Department of Chemistry
2024
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