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Investigation of the underlying, modifiable and non-modifiable risk factors for gestational diabetes among women living in Cape Town
Gestational Diabetes Mellitus has adverse effects in pregnancy that affects both the mother and infant. These complications include preeclampsia, macrosomia, preterm birth and risk of developing type 2 diabetes later in life. Understanding the risk factors for GDM is important in order to come up wi...
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| Format: | Thesis |
| Language: | Eng |
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Department of Human Biology
2024
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| _version_ | 1867613215378112512 |
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| access_status_str | Open Access |
| author | Koech, Elzie |
| author2 | Harbron, Janetta |
| author_browse | Harbron, Janetta Koech, Elzie |
| author_facet | Harbron, Janetta Koech, Elzie |
| author_sort | Koech, Elzie |
| collection | Thesis |
| description | Gestational Diabetes Mellitus has adverse effects in pregnancy that affects both the mother and infant. These complications include preeclampsia, macrosomia, preterm birth and risk of developing type 2 diabetes later in life. Understanding the risk factors for GDM is important in order to come up with intervention programs. This study aimed to determine the underlying modifiable, non-modifiable and intermediate risk factors of GDM for women living in Cape Town South Africa. We also compared lifestyle factors between women after diagnosis of GDM and women without GDM. Methods: We conducted a case control study among women living in Cape Town. Cases were defined as women diagnosed with GDM recruited at Groote Schuur Hospital while controls were women without GDM recruited from Vanguard clinic. Questionnaires and medical record review were used to collect data. The association between GDM and both risk factors and lifestyle variables was analysed using multivariable logistic regressions, with GDM as a binary outcome variable. Results: A total of 167 cases and 199 controls were included in the study. The mean age of cases was 32.5 years (28.0-37.0) and the mean age of controls was 25 years (22.0-31.0). In adjusted analyses, the risk factors for GDM were; family history of diabetes mellitus (OR 3.10, 95% CI 1.45-6.61, p =003), (MUAC) (OR 1.17, 95% CI 1.04-1.31, p =0.008) and stillbirth (OR 11.61, 95% CI 1.04-129.90, p =0.047), and BMI (OR 1.11, 95% CI 1.05-1.17, p |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/39619 |
| institution | University of Cape Town (South Africa) |
| language | Eng |
| last_indexed | 2026-06-10T12:32:36.207Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Department of Human Biology |
| publisherStr | Department of Human Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/39619 Investigation of the underlying, modifiable and non-modifiable risk factors for gestational diabetes among women living in Cape Town Koech, Elzie Harbron, Janetta Human Biology Gestational Diabetes Mellitus has adverse effects in pregnancy that affects both the mother and infant. These complications include preeclampsia, macrosomia, preterm birth and risk of developing type 2 diabetes later in life. Understanding the risk factors for GDM is important in order to come up with intervention programs. This study aimed to determine the underlying modifiable, non-modifiable and intermediate risk factors of GDM for women living in Cape Town South Africa. We also compared lifestyle factors between women after diagnosis of GDM and women without GDM. Methods: We conducted a case control study among women living in Cape Town. Cases were defined as women diagnosed with GDM recruited at Groote Schuur Hospital while controls were women without GDM recruited from Vanguard clinic. Questionnaires and medical record review were used to collect data. The association between GDM and both risk factors and lifestyle variables was analysed using multivariable logistic regressions, with GDM as a binary outcome variable. Results: A total of 167 cases and 199 controls were included in the study. The mean age of cases was 32.5 years (28.0-37.0) and the mean age of controls was 25 years (22.0-31.0). In adjusted analyses, the risk factors for GDM were; family history of diabetes mellitus (OR 3.10, 95% CI 1.45-6.61, p =003), (MUAC) (OR 1.17, 95% CI 1.04-1.31, p =0.008) and stillbirth (OR 11.61, 95% CI 1.04-129.90, p =0.047), and BMI (OR 1.11, 95% CI 1.05-1.17, p 2024-05-14T13:05:30Z 2024-05-14T13:05:30Z 2023 2024-05-07T13:16:08Z Thesis / Dissertation Masters http://hdl.handle.net/11427/39619 Eng application/pdf Department of Human Biology Faculty of Health Sciences |
| spellingShingle | Human Biology Koech, Elzie Investigation of the underlying, modifiable and non-modifiable risk factors for gestational diabetes among women living in Cape Town |
| thesis_degree_str | Master's |
| title | Investigation of the underlying, modifiable and non-modifiable risk factors for gestational diabetes among women living in Cape Town |
| title_full | Investigation of the underlying, modifiable and non-modifiable risk factors for gestational diabetes among women living in Cape Town |
| title_fullStr | Investigation of the underlying, modifiable and non-modifiable risk factors for gestational diabetes among women living in Cape Town |
| title_full_unstemmed | Investigation of the underlying, modifiable and non-modifiable risk factors for gestational diabetes among women living in Cape Town |
| title_short | Investigation of the underlying, modifiable and non-modifiable risk factors for gestational diabetes among women living in Cape Town |
| title_sort | investigation of the underlying modifiable and non modifiable risk factors for gestational diabetes among women living in cape town |
| topic | Human Biology |
| url | http://hdl.handle.net/11427/39619 |
| work_keys_str_mv | AT koechelzie investigationoftheunderlyingmodifiableandnonmodifiableriskfactorsforgestationaldiabetesamongwomenlivingincapetown |