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The identification of cytotoxic T lymphocyte (CTL) escape in a large, longitudinal subtype C HIV-1 sequence dataset
Human Immunodeficiency Virus (HIV) rapidly escapes cytotoxic T-cell lymphocyte (CTL) immune responses exerted by the host. Mutation patterns and HLA associated footprints linked to viral escape have been identified, making it possible to use viral sequence data, combined with the host HLA allele inf...
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| Format: | Thesis |
| Language: | English |
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Computational Biology Division
2024
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