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Postnatal Clubs: Implementation Of A Differentiated And Integrated Model Of Care For Mothers Living With Hiv And Their HIV-Exposed Uninfected Babies

Background Despite the reduction in the HIV mother-to-child transmission (MTCT) rate in South Africa, there are ongoing concerns in the breastfeeding period, linked to poor retention in care. To improve this retention, Post Natal Clubs (PNC) were created as an integrated, differentiated model of car...

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Main Author: Nelson, Aurelie
Other Authors: Myer, Benjamin
Format: Thesis
Language:English
Published: Department of Public Health and Family Medicine 2024
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access_status_str Open Access
author Nelson, Aurelie
author2 Myer, Benjamin
author_browse Myer, Benjamin
Nelson, Aurelie
author_facet Myer, Benjamin
Nelson, Aurelie
author_sort Nelson, Aurelie
collection Thesis
description Background Despite the reduction in the HIV mother-to-child transmission (MTCT) rate in South Africa, there are ongoing concerns in the breastfeeding period, linked to poor retention in care. To improve this retention, Post Natal Clubs (PNC) were created as an integrated, differentiated model of care providing psychosocial support and comprehensive care for the mother-infant pairs (MIP). We describe the implementation of PNC and examine its health outcomes in a peri-urban primary health care setting in Cape Town, South Africa. Methods In this cohort study, conducted between June 2016 and December 2019, MIPs were recruited into PNC between 6 weeks and 6 months of age and followed-up until 18 months of age. PNC MIPs were compared to a historical control group from the same setting. Outcomes included maternal Viral Load (VL), HIV testing at 9 and 18 months of age, and other maternal and child health outcomes. Results During the implementation of PNC study period, n=484 MIP were recruited with 84% overall attendance, 95% overall viral load suppression, and 98% overall uptake of HIV infant testing. Compared to historical controls, the PNC infant rapid test completion was 1.6 times higher (95% CI: 1.4-1.9) at 9 months and 2.0 times higher at 18 months (95% CI: 1.6-2.6). Through 12 months and between 12-18 months, maternal VL completion was higher in the PNC group compared to the historical control by 1.5 times (95% CI: 1.3-1.6) and 2.6 times (95% CI: 2.1- 3.2), respectively, with similar maternal VL suppression. Of 105 infants attending the 12 months visit, 99% were fully vaccinated by one year. Conclusion MIP in the PNC showed better PMTCT outcomes than historical controls with high levels of retention in care. Other outcomes such as immunisation results suggest that integration of services, such as in the PNC, is feasible and beneficial for MIPs.
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provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
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spelling oai:open.uct.ac.za:11427/39771 Postnatal Clubs: Implementation Of A Differentiated And Integrated Model Of Care For Mothers Living With Hiv And Their HIV-Exposed Uninfected Babies Nelson, Aurelie Myer, Benjamin Public Health and Family Medicine Background Despite the reduction in the HIV mother-to-child transmission (MTCT) rate in South Africa, there are ongoing concerns in the breastfeeding period, linked to poor retention in care. To improve this retention, Post Natal Clubs (PNC) were created as an integrated, differentiated model of care providing psychosocial support and comprehensive care for the mother-infant pairs (MIP). We describe the implementation of PNC and examine its health outcomes in a peri-urban primary health care setting in Cape Town, South Africa. Methods In this cohort study, conducted between June 2016 and December 2019, MIPs were recruited into PNC between 6 weeks and 6 months of age and followed-up until 18 months of age. PNC MIPs were compared to a historical control group from the same setting. Outcomes included maternal Viral Load (VL), HIV testing at 9 and 18 months of age, and other maternal and child health outcomes. Results During the implementation of PNC study period, n=484 MIP were recruited with 84% overall attendance, 95% overall viral load suppression, and 98% overall uptake of HIV infant testing. Compared to historical controls, the PNC infant rapid test completion was 1.6 times higher (95% CI: 1.4-1.9) at 9 months and 2.0 times higher at 18 months (95% CI: 1.6-2.6). Through 12 months and between 12-18 months, maternal VL completion was higher in the PNC group compared to the historical control by 1.5 times (95% CI: 1.3-1.6) and 2.6 times (95% CI: 2.1- 3.2), respectively, with similar maternal VL suppression. Of 105 infants attending the 12 months visit, 99% were fully vaccinated by one year. Conclusion MIP in the PNC showed better PMTCT outcomes than historical controls with high levels of retention in care. Other outcomes such as immunisation results suggest that integration of services, such as in the PNC, is feasible and beneficial for MIPs. 2024-05-30T09:46:03Z 2024-05-30T09:46:03Z 2023 2024-05-28T08:53:51Z Thesis / Dissertation Masters MPH http://hdl.handle.net/11427/39771 eng application/pdf Department of Public Health and Family Medicine Faculty of Health Sciences
spellingShingle Public Health and Family Medicine
Nelson, Aurelie
Postnatal Clubs: Implementation Of A Differentiated And Integrated Model Of Care For Mothers Living With Hiv And Their HIV-Exposed Uninfected Babies
thesis_degree_str Master's
title Postnatal Clubs: Implementation Of A Differentiated And Integrated Model Of Care For Mothers Living With Hiv And Their HIV-Exposed Uninfected Babies
title_full Postnatal Clubs: Implementation Of A Differentiated And Integrated Model Of Care For Mothers Living With Hiv And Their HIV-Exposed Uninfected Babies
title_fullStr Postnatal Clubs: Implementation Of A Differentiated And Integrated Model Of Care For Mothers Living With Hiv And Their HIV-Exposed Uninfected Babies
title_full_unstemmed Postnatal Clubs: Implementation Of A Differentiated And Integrated Model Of Care For Mothers Living With Hiv And Their HIV-Exposed Uninfected Babies
title_short Postnatal Clubs: Implementation Of A Differentiated And Integrated Model Of Care For Mothers Living With Hiv And Their HIV-Exposed Uninfected Babies
title_sort postnatal clubs implementation of a differentiated and integrated model of care for mothers living with hiv and their hiv exposed uninfected babies
topic Public Health and Family Medicine
url http://hdl.handle.net/11427/39771
work_keys_str_mv AT nelsonaurelie postnatalclubsimplementationofadifferentiatedandintegratedmodelofcareformotherslivingwithhivandtheirhivexposeduninfectedbabies