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Utility of EEG in the diagnosis of Efavirenz neurotoxity in HIV positive patients at a South African tertiary hospital

Background: Efavirenz (EFV) is a widely used antiretroviral medication in HIV treatment, primarily metabolized by cytochrome P450 CYP2B6, an enzyme whose loss of function polymorphisms have been associated with risk of EFV neurotoxicity. Patients with late onset efavirenz neurotoxicity syndrome (LEN...

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Bibliographic Details
Main Author: Ssemmanda, Salvatore
Other Authors: Leepan, Edward
Format: Thesis
Language:English
Published: Department of Medicine 2024
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