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The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa
rhe scope of this work needs some explanation. I first became interested in the sickle-cell anomaly in 1951, while employed as a medical officer to an asbestos r::iining group in Southern .Rhodesia. Here I had :for investigation a population of several thousand adult male Bantu, very mixed as to tri...
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| Format: | Thesis |
| Language: | English |
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Department of Medicine
2024
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| _version_ | 1867613146582089728 |
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| access_status_str | Open Access |
| author | Peter Brain |
| author_browse | Peter Brain |
| author_facet | Peter Brain |
| author_sort | Peter Brain |
| collection | Thesis |
| description | rhe scope of this work needs some explanation. I first became interested in the sickle-cell anomaly in 1951, while employed as a medical officer to an asbestos r::iining group in Southern .Rhodesia. Here I had :for investigation a population of several thousand adult male Bantu, very mixed as to tribe, drawn from a wide area of south Central Africa. The scope of this invest1gs,tion has been determined by the nature of the nmterial; vvbich is in some respects unusual. This will be fully described later, but the important point is that in this population sickle-cell anaemia, if it occurs at all, is very rare. The sickle-cell trait, on the other hand, is frequently seen, and in a fit adult population of this kind it appears to exist virtually unadulterated by cases of sickle-cell anaemia either active or latent. This makes the population a peculiarly advantageous one for a study of the trait in its pure form, and it is the trait, and not the anaemia, that is dealt with in this thesis. The anaemia is treated only incidentally, and I should ffiake it clear at the beginning that I can express no IL authoritative views on it. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/40239 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:30.019Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/40239 The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa Peter Brain Medicine rhe scope of this work needs some explanation. I first became interested in the sickle-cell anomaly in 1951, while employed as a medical officer to an asbestos r::iining group in Southern .Rhodesia. Here I had :for investigation a population of several thousand adult male Bantu, very mixed as to tribe, drawn from a wide area of south Central Africa. The scope of this invest1gs,tion has been determined by the nature of the nmterial; vvbich is in some respects unusual. This will be fully described later, but the important point is that in this population sickle-cell anaemia, if it occurs at all, is very rare. The sickle-cell trait, on the other hand, is frequently seen, and in a fit adult population of this kind it appears to exist virtually unadulterated by cases of sickle-cell anaemia either active or latent. This makes the population a peculiarly advantageous one for a study of the trait in its pure form, and it is the trait, and not the anaemia, that is dealt with in this thesis. The anaemia is treated only incidentally, and I should ffiake it clear at the beginning that I can express no IL authoritative views on it. 2024-07-02T10:29:54Z 2024-07-02T10:29:54Z 1953 2024-06-25T12:30:40Z Thesis / Dissertation Doctoral PhD http://hdl.handle.net/11427/40239 eng application/pdf Department of Medicine Faculty of Health Sciences |
| spellingShingle | Medicine Peter Brain The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa |
| thesis_degree_str | Doctoral |
| title | The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa |
| title_full | The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa |
| title_fullStr | The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa |
| title_full_unstemmed | The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa |
| title_short | The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa |
| title_sort | sickle cell trait a study of its distribution and effects in some bantu tribes of south central africa |
| topic | Medicine |
| url | http://hdl.handle.net/11427/40239 |
| work_keys_str_mv | AT peterbrain thesicklecelltraitastudyofitsdistributionandeffectsinsomebantutribesofsouthcentralafrica AT peterbrain sicklecelltraitastudyofitsdistributionandeffectsinsomebantutribesofsouthcentralafrica |