Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
The predictors and patterns of alcohol use in HIV positive women during their postpartum period, and how these impact viral load.
Introduction Although alcohol use among HIV-positive pregnant women in South Africa has been extensively researched, few studies have attempted to understand the longitudinal patterns and predictors of alcohol use when HIV-positive status intersects with the postpartum period. We examined the patter...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | Eng |
| Published: |
Department of Public Health and Family Medicine
2024
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613205051736064 |
|---|---|
| access_status_str | Open Access |
| author | Mazubane, Thandeka |
| author2 | Myer, Benjamin |
| author_browse | Mazubane, Thandeka Myer, Benjamin |
| author_facet | Myer, Benjamin Mazubane, Thandeka |
| author_sort | Mazubane, Thandeka |
| collection | Thesis |
| description | Introduction Although alcohol use among HIV-positive pregnant women in South Africa has been extensively researched, few studies have attempted to understand the longitudinal patterns and predictors of alcohol use when HIV-positive status intersects with the postpartum period. We examined the patterns of alcohol consumption during the postpartum period among HIV-positive women from Gugulethu, Cape Town; explored predictors associated with any alcohol consumption; and lastly, examined the association between alcohol use and HIV viral load. Methods Participants were recruited at the Gugulethu Community Health Centre while receiving prevention of mother to child transmission (PMTCT) services, obstetric, or postnatal care. The Alcohol Use Disorder Identification Test (AUDIT) screening tool was used to assess the alcohol use of eligible women. Participants were also assessed for hazardous alcohol use using the AUDIT-C scoring system during the analysis. The factors associated with patterns of alcohol use were then investigated using multiple logic regression and Generalised Mixed Effect Models. Using Generalised Mixed Effect Models, we also investigated the relationship between alcohol consumption and HIV viral load. Results Among 360 women (median age: 33 years), 10–28% reported alcohol use during the 24-month postpartum period, with alcohol use characterised by hazardous, binge drinking, and risky/dependency behaviour and associated with single relationship status and depression, whereas strong social support and patient-provider relationship was protective against risky/dependent alcohol use. We also found an association between hazardous, risky/dependent alcohol use and viral load, where hazardous drinkers and risky/dependent were 3 and 5 times more likely to have a suboptimal (>1000 copies/ml) viral load, respectively. Conclusion These unique data sheds light on the trajectories of alcohol use during the postpartum period in this vulnerable population, emphasizing the critical support and attention needed by this population and the strong focus public health needs to put on screening and interventions at a primary care level. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/40561 |
| institution | University of Cape Town (South Africa) |
| language | Eng |
| last_indexed | 2026-06-10T12:32:26.116Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Department of Public Health and Family Medicine |
| publisherStr | Department of Public Health and Family Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/40561 The predictors and patterns of alcohol use in HIV positive women during their postpartum period, and how these impact viral load. Mazubane, Thandeka Myer, Benjamin Public Health and Family Medicine Introduction Although alcohol use among HIV-positive pregnant women in South Africa has been extensively researched, few studies have attempted to understand the longitudinal patterns and predictors of alcohol use when HIV-positive status intersects with the postpartum period. We examined the patterns of alcohol consumption during the postpartum period among HIV-positive women from Gugulethu, Cape Town; explored predictors associated with any alcohol consumption; and lastly, examined the association between alcohol use and HIV viral load. Methods Participants were recruited at the Gugulethu Community Health Centre while receiving prevention of mother to child transmission (PMTCT) services, obstetric, or postnatal care. The Alcohol Use Disorder Identification Test (AUDIT) screening tool was used to assess the alcohol use of eligible women. Participants were also assessed for hazardous alcohol use using the AUDIT-C scoring system during the analysis. The factors associated with patterns of alcohol use were then investigated using multiple logic regression and Generalised Mixed Effect Models. Using Generalised Mixed Effect Models, we also investigated the relationship between alcohol consumption and HIV viral load. Results Among 360 women (median age: 33 years), 10–28% reported alcohol use during the 24-month postpartum period, with alcohol use characterised by hazardous, binge drinking, and risky/dependency behaviour and associated with single relationship status and depression, whereas strong social support and patient-provider relationship was protective against risky/dependent alcohol use. We also found an association between hazardous, risky/dependent alcohol use and viral load, where hazardous drinkers and risky/dependent were 3 and 5 times more likely to have a suboptimal (>1000 copies/ml) viral load, respectively. Conclusion These unique data sheds light on the trajectories of alcohol use during the postpartum period in this vulnerable population, emphasizing the critical support and attention needed by this population and the strong focus public health needs to put on screening and interventions at a primary care level. 2024-10-08T10:29:33Z 2024-10-08T10:29:33Z 2023 2024-05-16T13:24:06Z Thesis / Dissertation Masters MPH http://hdl.handle.net/11427/40561 Eng application/pdf Department of Public Health and Family Medicine Faculty of Health Sciences |
| spellingShingle | Public Health and Family Medicine Mazubane, Thandeka The predictors and patterns of alcohol use in HIV positive women during their postpartum period, and how these impact viral load. |
| thesis_degree_str | Master's |
| title | The predictors and patterns of alcohol use in HIV positive women during their postpartum period, and how these impact viral load. |
| title_full | The predictors and patterns of alcohol use in HIV positive women during their postpartum period, and how these impact viral load. |
| title_fullStr | The predictors and patterns of alcohol use in HIV positive women during their postpartum period, and how these impact viral load. |
| title_full_unstemmed | The predictors and patterns of alcohol use in HIV positive women during their postpartum period, and how these impact viral load. |
| title_short | The predictors and patterns of alcohol use in HIV positive women during their postpartum period, and how these impact viral load. |
| title_sort | predictors and patterns of alcohol use in hiv positive women during their postpartum period and how these impact viral load |
| topic | Public Health and Family Medicine |
| url | http://hdl.handle.net/11427/40561 |
| work_keys_str_mv | AT mazubanethandeka thepredictorsandpatternsofalcoholuseinhivpositivewomenduringtheirpostpartumperiodandhowtheseimpactviralload AT mazubanethandeka predictorsandpatternsofalcoholuseinhivpositivewomenduringtheirpostpartumperiodandhowtheseimpactviralload |