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Presentation and management of snakebite envenomation in the uMkhanyakude district of KwaZulu-Natal (Mosvold Hospital)

Background. Snakebites have been recognized as a neglected tropical disease by the World Health Organization (WHO) since 2009, and in 2017, was elevated to category A. South Africa (SA) has a well documented prevalence of snakebites, and there has been a recent surge in attention due to dwindling an...

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Main Author: Kabeya, Matamba Jean Benoit
Other Authors: Hodkinson, Peter
Format: Thesis
Language:English
Published: Division of Emergency Medicine 2025
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access_status_str Open Access
author Kabeya, Matamba Jean Benoit
author2 Hodkinson, Peter
author_browse Hodkinson, Peter
Kabeya, Matamba Jean Benoit
author_facet Hodkinson, Peter
Kabeya, Matamba Jean Benoit
author_sort Kabeya, Matamba Jean Benoit
collection Thesis
description Background. Snakebites have been recognized as a neglected tropical disease by the World Health Organization (WHO) since 2009, and in 2017, was elevated to category A. South Africa (SA) has a well documented prevalence of snakebites, and there has been a recent surge in attention due to dwindling antivenom stocks. uMkhanyakude District in the far northeast of SA is known to use more antivenoms than elsewhere in SA, and thus seemingly to have the highest incidence of venomous snakebites in SA, yet no recent study has come from this district to describe snakebite management. Although there are various protocols and guidelines, as well as tools for assessing severity, none are standardized and it remains unclear what local management (and outcomes) are, particularly at the level of a small district hospital with arguably the highest incidence of snake bites in SA. Methods This study is a descriptive, retrospective observational study, describing all victims of snakebites presenting from 01st September 2019 to 31st August 2022 to a district hospital, Mosvold Hospital. Data was collected from patient's medical records. Information about demographics, clinical presentations, treatments and outcomes was collected and analysed. Results Some 155 snakebite cases presented, including 81 women (52.26%) and 74 men (47.74%). The incidence rate was 58 snakebite cases per 100000 people per years. Most patients were young, with a median age of 19 years (range 0-94 years), and most bites occurred outdoors (48.70%). Patients were most often bitten on the lower limb (69.03%), and most presented with minimal swelling - 117 patients (75.48%). Antivenom was administered to 33 patients (21.29%), and 24 (72.73%) of those who received antivenom experienced some form of post-antivenom reaction. Three patients died during their hospital stay, resulting in a mortality rate of 1.2 deaths per 100000 people per years.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:31:45.395Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2025
publishDateRange 2025
publishDateSort 2025
publisher Division of Emergency Medicine
publisherStr Division of Emergency Medicine
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/41000 Presentation and management of snakebite envenomation in the uMkhanyakude district of KwaZulu-Natal (Mosvold Hospital) Kabeya, Matamba Jean Benoit Hodkinson, Peter Wood, Darryl snakebite envenomation uMkhanyakude district KwaZulu-Natal Mosvold Hospital Background. Snakebites have been recognized as a neglected tropical disease by the World Health Organization (WHO) since 2009, and in 2017, was elevated to category A. South Africa (SA) has a well documented prevalence of snakebites, and there has been a recent surge in attention due to dwindling antivenom stocks. uMkhanyakude District in the far northeast of SA is known to use more antivenoms than elsewhere in SA, and thus seemingly to have the highest incidence of venomous snakebites in SA, yet no recent study has come from this district to describe snakebite management. Although there are various protocols and guidelines, as well as tools for assessing severity, none are standardized and it remains unclear what local management (and outcomes) are, particularly at the level of a small district hospital with arguably the highest incidence of snake bites in SA. Methods This study is a descriptive, retrospective observational study, describing all victims of snakebites presenting from 01st September 2019 to 31st August 2022 to a district hospital, Mosvold Hospital. Data was collected from patient's medical records. Information about demographics, clinical presentations, treatments and outcomes was collected and analysed. Results Some 155 snakebite cases presented, including 81 women (52.26%) and 74 men (47.74%). The incidence rate was 58 snakebite cases per 100000 people per years. Most patients were young, with a median age of 19 years (range 0-94 years), and most bites occurred outdoors (48.70%). Patients were most often bitten on the lower limb (69.03%), and most presented with minimal swelling - 117 patients (75.48%). Antivenom was administered to 33 patients (21.29%), and 24 (72.73%) of those who received antivenom experienced some form of post-antivenom reaction. Three patients died during their hospital stay, resulting in a mortality rate of 1.2 deaths per 100000 people per years. 2025-02-21T11:12:31Z 2025-02-21T11:12:31Z 2024 2025-02-21T11:10:52Z Thesis / Dissertation Masters MPhil http://hdl.handle.net/11427/41000 eng application/pdf Division of Emergency Medicine Faculty of Health Sciences University of Cape Town
spellingShingle snakebite envenomation
uMkhanyakude district
KwaZulu-Natal
Mosvold Hospital
Kabeya, Matamba Jean Benoit
Presentation and management of snakebite envenomation in the uMkhanyakude district of KwaZulu-Natal (Mosvold Hospital)
thesis_degree_str Master's
title Presentation and management of snakebite envenomation in the uMkhanyakude district of KwaZulu-Natal (Mosvold Hospital)
title_full Presentation and management of snakebite envenomation in the uMkhanyakude district of KwaZulu-Natal (Mosvold Hospital)
title_fullStr Presentation and management of snakebite envenomation in the uMkhanyakude district of KwaZulu-Natal (Mosvold Hospital)
title_full_unstemmed Presentation and management of snakebite envenomation in the uMkhanyakude district of KwaZulu-Natal (Mosvold Hospital)
title_short Presentation and management of snakebite envenomation in the uMkhanyakude district of KwaZulu-Natal (Mosvold Hospital)
title_sort presentation and management of snakebite envenomation in the umkhanyakude district of kwazulu natal mosvold hospital
topic snakebite envenomation
uMkhanyakude district
KwaZulu-Natal
Mosvold Hospital
url http://hdl.handle.net/11427/41000
work_keys_str_mv AT kabeyamatambajeanbenoit presentationandmanagementofsnakebiteenvenomationintheumkhanyakudedistrictofkwazulunatalmosvoldhospital