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Social determinants of art adherence among adolescent and young pregnant and postpartum women living with HIV in Cape Town, South Africa
Women living with HIV in South Africa are at risk of poor antiretroviral therapy (ART) adherence during and after pregnancy. Adolescents have lower adherence rates than other age groups and experience several barriers to adherence. Pregnancy and postpartum periods also present unique obstacles. We a...
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| Format: | Thesis |
| Language: | Eng |
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Department of Public Health and Family Medicine
2025
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| _version_ | 1867613224356020224 |
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| access_status_str | Open Access |
| author | Mosigi, Popo |
| author2 | Phillips, Tamsin |
| author_browse | Mosigi, Popo Phillips, Tamsin |
| author_facet | Phillips, Tamsin Mosigi, Popo |
| author_sort | Mosigi, Popo |
| collection | Thesis |
| description | Women living with HIV in South Africa are at risk of poor antiretroviral therapy (ART) adherence during and after pregnancy. Adolescents have lower adherence rates than other age groups and experience several barriers to adherence. Pregnancy and postpartum periods also present unique obstacles. We assessed the association between social determinants of health and ART adherence (using a three-item self-report adherence scale and reported missed ART doses) among 100 pregnant and postpartum women aged 16-24 years and on ART in Gugulethu, Cape Town. Overall, 72% of women scored ≤95% on the adherence scale (69% and 75% among pregnant and postpartum women, respectively p=0.533) and 22% of women reported missing ≥1 day of ART in the past 30 days (31% and 15% among pregnant and postpartum women, respectively p=0.050). An adherence score ≤95% versus >95% was associated with lower employment (32% versus 50%, p=0.093) and slightly lower social connectedness scores (mean 4.71 versus 4.97, p=0.084). No demographic or social characteristics were statistically significantly associated with adherence in multivariable models. These findings highlight nuances to measuring self-reported ART adherence. Larger studies are needed to further explore adherence challenges and the role of social connection and adherence among young pregnant and postpartum women living with HIV in South Africa. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/41165 |
| institution | University of Cape Town (South Africa) |
| language | Eng |
| last_indexed | 2026-06-10T12:32:44.899Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Department of Public Health and Family Medicine |
| publisherStr | Department of Public Health and Family Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/41165 Social determinants of art adherence among adolescent and young pregnant and postpartum women living with HIV in Cape Town, South Africa Mosigi, Popo Phillips, Tamsin Medicine Women living with HIV in South Africa are at risk of poor antiretroviral therapy (ART) adherence during and after pregnancy. Adolescents have lower adherence rates than other age groups and experience several barriers to adherence. Pregnancy and postpartum periods also present unique obstacles. We assessed the association between social determinants of health and ART adherence (using a three-item self-report adherence scale and reported missed ART doses) among 100 pregnant and postpartum women aged 16-24 years and on ART in Gugulethu, Cape Town. Overall, 72% of women scored ≤95% on the adherence scale (69% and 75% among pregnant and postpartum women, respectively p=0.533) and 22% of women reported missing ≥1 day of ART in the past 30 days (31% and 15% among pregnant and postpartum women, respectively p=0.050). An adherence score ≤95% versus >95% was associated with lower employment (32% versus 50%, p=0.093) and slightly lower social connectedness scores (mean 4.71 versus 4.97, p=0.084). No demographic or social characteristics were statistically significantly associated with adherence in multivariable models. These findings highlight nuances to measuring self-reported ART adherence. Larger studies are needed to further explore adherence challenges and the role of social connection and adherence among young pregnant and postpartum women living with HIV in South Africa. 2025-03-13T11:17:56Z 2025-03-13T11:17:56Z 2024 2025-03-13T11:13:02Z Thesis / Dissertation Masters MPH http://hdl.handle.net/11427/41165 Eng application/pdf Department of Public Health and Family Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Mosigi, Popo Social determinants of art adherence among adolescent and young pregnant and postpartum women living with HIV in Cape Town, South Africa |
| thesis_degree_str | Master's |
| title | Social determinants of art adherence among adolescent and young pregnant and postpartum women living with HIV in Cape Town, South Africa |
| title_full | Social determinants of art adherence among adolescent and young pregnant and postpartum women living with HIV in Cape Town, South Africa |
| title_fullStr | Social determinants of art adherence among adolescent and young pregnant and postpartum women living with HIV in Cape Town, South Africa |
| title_full_unstemmed | Social determinants of art adherence among adolescent and young pregnant and postpartum women living with HIV in Cape Town, South Africa |
| title_short | Social determinants of art adherence among adolescent and young pregnant and postpartum women living with HIV in Cape Town, South Africa |
| title_sort | social determinants of art adherence among adolescent and young pregnant and postpartum women living with hiv in cape town south africa |
| topic | Medicine |
| url | http://hdl.handle.net/11427/41165 |
| work_keys_str_mv | AT mosigipopo socialdeterminantsofartadherenceamongadolescentandyoungpregnantandpostpartumwomenlivingwithhivincapetownsouthafrica |