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Modelling and validation of bacterial O-antigen conformations: ring puckering in Shigella flexneri 7a and 7b O-antigens as a case study

This work forms part of a larger project investigating the conformation and dynamics of Shigella flexneri O-antigens. S. flexneri is a leading cause of diarrhoeal related diseases, especially in Sub-Saharan Africa and Southeast Asia. There are over 30 S. flexneri serotypes and, with the exception of...

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Bibliographic Details
Main Author: Timol, Zaheer
Other Authors: Kuttel, Michelle
Format: Thesis
Language:English
Eng
Published: Department of Computer Science 2025
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