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Nuclear respiratory factor 1: a novel inhibitor of the human gene promoter of the cardiac isoform of acetyl-coenzyme a carboxylase
Introduction: Nuclear respiratory factor-1 (NRF-1) is a pivotal transcriptional modulator controlling the expression of nuclear genes encoding mitochondrial proteins. Activation of 5'-AMP-activated protein kinase (AMPK) has been associated with enhanced NRF-1 gene promoter binding activity. Furtherm...
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| Format: | Thesis |
| Language: | English English |
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Department of Medicine
2025
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