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Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country
Background: Acute coronary syndrome (ACS) has become a leading cause of death in low-and middle-income countries. There is a lack of data regarding the outcomes of ACS in Africa. This study aims to assess the outcomes of ACS patients admitted to a resource-limited district hospital in Cape Town, Sou...
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| Format: | Thesis |
| Language: | English English |
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Department of Medicine
2025
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| _version_ | 1867613235211927552 |
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| access_status_str | Open Access |
| author | Govender, Kamini |
| author2 | Van Der Schyff, Nasief |
| author_browse | Govender, Kamini Van Der Schyff, Nasief |
| author_facet | Van Der Schyff, Nasief Govender, Kamini |
| author_sort | Govender, Kamini |
| collection | Thesis |
| description | Background: Acute coronary syndrome (ACS) has become a leading cause of death in low-and middle-income countries. There is a lack of data regarding the outcomes of ACS in Africa. This study aims to assess the outcomes of ACS patients admitted to a resource-limited district hospital in Cape Town, South Africa. Methods: We conducted a retrospective observational study of patients admitted with ACS to the Department of Medicine at Victoria Hospital, Cape Town, from the 1 st September 2020 to 30 November 2020. Results: Eighty eight patients with a diagnosis of ACS was admitted, of who 52 had NSTEMI/UAP and 36 patients had STEMI. The median age was 60 years, with a male predominance of 61.36%. The major risk factors for CAD were hypertension and smoking. The overall 1-month, 6-month, and 12-month mortality rates for our cohort were 4%, 17%, and 19%, respectively. Patients that received coronary intervention (thrombolytics/PCI/CABG) had better outcomes than in those who were managed conservatively. Conclusion: This study describes the experience of ACS management in a resource-limited public hospital in Cape Town, South Africa. Our patients had multiple cardiovascular risk factors with a higher mortality than published data. The lack of receiving coronary intervention was associated with worse outcomes. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/42299 |
| institution | University of Cape Town (South Africa) |
| language | English eng |
| last_indexed | 2026-06-10T12:32:54.720Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/42299 Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country Govender, Kamini Van Der Schyff, Nasief Engel, Mark acute coronary syndrome outcomes ischemic heart disease mortality MACE Background: Acute coronary syndrome (ACS) has become a leading cause of death in low-and middle-income countries. There is a lack of data regarding the outcomes of ACS in Africa. This study aims to assess the outcomes of ACS patients admitted to a resource-limited district hospital in Cape Town, South Africa. Methods: We conducted a retrospective observational study of patients admitted with ACS to the Department of Medicine at Victoria Hospital, Cape Town, from the 1 st September 2020 to 30 November 2020. Results: Eighty eight patients with a diagnosis of ACS was admitted, of who 52 had NSTEMI/UAP and 36 patients had STEMI. The median age was 60 years, with a male predominance of 61.36%. The major risk factors for CAD were hypertension and smoking. The overall 1-month, 6-month, and 12-month mortality rates for our cohort were 4%, 17%, and 19%, respectively. Patients that received coronary intervention (thrombolytics/PCI/CABG) had better outcomes than in those who were managed conservatively. Conclusion: This study describes the experience of ACS management in a resource-limited public hospital in Cape Town, South Africa. Our patients had multiple cardiovascular risk factors with a higher mortality than published data. The lack of receiving coronary intervention was associated with worse outcomes. 2025-11-21T13:03:48Z 2025-11-21T13:03:48Z 2025 2025-11-21T13:00:19Z Thesis / Dissertation Masters MMed http://hdl.handle.net/11427/42299 en eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | acute coronary syndrome outcomes ischemic heart disease mortality MACE Govender, Kamini Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country |
| thesis_degree_str | Master's |
| title | Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country |
| title_full | Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country |
| title_fullStr | Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country |
| title_full_unstemmed | Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country |
| title_short | Outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country |
| title_sort | outcomes of patients admitted with acute coronary syndrome to a district level hospital in a lower to middle income country |
| topic | acute coronary syndrome outcomes ischemic heart disease mortality MACE |
| url | http://hdl.handle.net/11427/42299 |
| work_keys_str_mv | AT govenderkamini outcomesofpatientsadmittedwithacutecoronarysyndrometoadistrictlevelhospitalinalowertomiddleincomecountry |