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Elucidation of the pathways underlying the spectrum of cancers affecting different tissues in lynch syndrome
Lynch Syndrome (LS) is a hereditary disorder that predisposes individuals to an increased risk of several cancers, particularly colorectal cancer (CRC) and endometrial cancer (EC). LS arises from constitutional (“germline”) pathogenic variants affecting one of four DNA mismatch repair (MMR) genes. W...
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| Language: | English English |
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Department of Pathology
2025
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