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Characterisation of a public T cell clonotype enriched in m.tb infected individuals who do not progress to tuberculosis

Introduction: T cells are known to play an important role in controlling M. Tuberculosis (M.tb) infection, but it is not known if specific T cell clones contribute to the outcome of M.tb infection. We recently completed a bulk T cell receptor (TCR) sequencing screen and observed that frequencies of...

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Main Author: Matela, Motshidisi
Other Authors: Musvosvi, Munyaradzi
Format: Thesis
Language:English
English
Published: Department of Pathology 2025
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