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Exploring topological data analysis in gene expression data topology-driven biomarker discovery and clinical outcome prediction in oncology

This thesis is grounded in the fundamental observation that biological data has shape and this shape matters. Beneath the high-dimensional, often noisy landscape of gene expression profiles lie hidden topological structures (connected components, loops and voids) that capture the complex relationshi...

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Bibliographic Details
Main Author: Nyase, Ndivhuwo
Other Authors: Mashatola, Lebohang
Format: Thesis
Language:English
English
Published: Department of Statistical Sciences 2026
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