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Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052
Summary in English.
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Department of Molecular and Cell Biology
2014
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| _version_ | 1867613316249026561 |
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| access_status_str | Open Access |
| author | Rafudeen, M S |
| author2 | Reid, Sharon J |
| author_browse | Rafudeen, M S Reid, Sharon J |
| author_facet | Reid, Sharon J Rafudeen, M S |
| author_sort | Rafudeen, M S |
| collection | Thesis |
| description | Summary in English. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/4326 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:10.861Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Molecular and Cell Biology |
| publisherStr | Department of Molecular and Cell Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/4326 Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052 Rafudeen, M S Reid, Sharon J Cell Biology Summary in English. Includes bibliographical references. The substrate basis for the industrial acetone-butanol-ethanol (ABE) fermentations, has been agricultural products rich in starch or sucrose, and employed taxonomically distinct amylolytic and saccharolytic solventogenic clostridial strains respectively. There is evidence to suggest that the utilization of these substrates is subject to carbon catabolite repression. In Gram-positive bacteria, carbon catabolite repression is controlled by a global regulatory mechanism, central to which is an imperfect palindromic sequence, the cre element, which is recognized by a protein of the GalR-LacI family, the CcpA protein. A ccpA homologue, regA, has been previously identified in C. acetobutylicum NCP262 and successfully complemented a B. subtilis ccpA mutant strain. The sucrose operon from C. beijerinckii NCIMB 8052, scrARBK, has been characterised at the physiological and genetic levels with the ScrR repressor found to negatively auto-regulate the operon. 2014-07-30T17:41:46Z 2014-07-30T17:41:46Z 2001 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/4326 eng application/pdf Department of Molecular and Cell Biology Faculty of Science University of Cape Town |
| spellingShingle | Cell Biology Rafudeen, M S Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052 |
| thesis_degree_str | Doctoral |
| title | Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052 |
| title_full | Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052 |
| title_fullStr | Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052 |
| title_full_unstemmed | Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052 |
| title_short | Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052 |
| title_sort | investigation of carbon catabolite repression in clostridium beijerinckii ncimb 8052 |
| topic | Cell Biology |
| url | http://hdl.handle.net/11427/4326 |
| work_keys_str_mv | AT rafudeenms investigationofcarboncataboliterepressioninclostridiumbeijerinckiincimb8052 |