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Development of candidate Human papillomavirus vaccines
Bibliography: leaves 180-218.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Department of Molecular and Cell Biology
2014
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| _version_ | 1867613187870818304 |
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| access_status_str | Open Access |
| author | Varsani, Arvind |
| author2 | Rybicki, Ed |
| author_browse | Rybicki, Ed Varsani, Arvind |
| author_facet | Rybicki, Ed Varsani, Arvind |
| author_sort | Varsani, Arvind |
| collection | Thesis |
| description | Bibliography: leaves 180-218. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/5970 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:09.918Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Molecular and Cell Biology |
| publisherStr | Department of Molecular and Cell Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/5970 Development of candidate Human papillomavirus vaccines Varsani, Arvind Rybicki, Ed Williamson, Anne-Lise Cell Biology Bibliography: leaves 180-218. The objective of this thesis was to investigate novel and plant-based vaccines against the Human papillomavirus type 16 (HPV-16), which is primarily responsible for cervical cancer. As a first study, the L1 gene of a South Africna variant of HPV-16 (L1 504) and a mutant (504[ΔA266T]), where the alanine at 266 was mutated to a threonine, were expressed in insect cells by recombinant baculovirus, and the resulting virus-like particles (VLPs) were tested with a panel of well-characterised monoclonal antibodies (Mabs). 2014-08-02T14:56:43Z 2014-08-02T14:56:43Z 2003 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/5970 eng application/pdf Department of Molecular and Cell Biology Faculty of Science University of Cape Town |
| spellingShingle | Cell Biology Varsani, Arvind Development of candidate Human papillomavirus vaccines |
| thesis_degree_str | Doctoral |
| title | Development of candidate Human papillomavirus vaccines |
| title_full | Development of candidate Human papillomavirus vaccines |
| title_fullStr | Development of candidate Human papillomavirus vaccines |
| title_full_unstemmed | Development of candidate Human papillomavirus vaccines |
| title_short | Development of candidate Human papillomavirus vaccines |
| title_sort | development of candidate human papillomavirus vaccines |
| topic | Cell Biology |
| url | http://hdl.handle.net/11427/5970 |
| work_keys_str_mv | AT varsaniarvind developmentofcandidatehumanpapillomavirusvaccines |