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Physicochemical study of solid Cyclodextrin inclusion complexes of the antithrombotic Ajoene
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Chemistry
2014
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| _version_ | 1867613546411458560 |
|---|---|
| access_status_str | Open Access |
| author | Smith, Vincent Joseph |
| author2 | Caira, Mino R |
| author_browse | Caira, Mino R Smith, Vincent Joseph |
| author_facet | Caira, Mino R Smith, Vincent Joseph |
| author_sort | Smith, Vincent Joseph |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/6293 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:37:52.185Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Chemistry |
| publisherStr | Department of Chemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/6293 Physicochemical study of solid Cyclodextrin inclusion complexes of the antithrombotic Ajoene Smith, Vincent Joseph Caira, Mino R Hunter, Roger Bourne, Susan Chemistry Includes bibliographical references. This study describes the preparation and physicochemical characterization of inclusion complexes formed between selected cyclodextrins (CDs) and ajoene, an antlthrombotlc found in garlic. The E and Z isomers of ajoene (4,5,9,-trithiadodeca-1,6,11-triene-9-oxide) were reacted with α, β, γ-CD heptakis(2,6-di-O-methyl )-β-CD (DIMEB) and heptakls(2, 3, 6-tri-O-methyl )-β-CD (TRIMEB) to yield inclusion compounds α-CD·(E)-ajoene (1), α-CD·(Z)ajoene (2), β-CD·(E)-ajoene (3), β-CD·(Z)-ajoene (4), y-CD·(E)-ajoene (5), y-CD·(Z)-ajoene (6), DIMEB·(E)-ajoene (7), DIMEB·(Z)-ajoene (6), TRIMEB·(E)-ajoene·05H20 (9) and TRIMEB·(Z)-ajoene (10). 2014-08-13T14:25:55Z 2014-08-13T14:25:55Z 2004 Master Thesis Masters MSc http://hdl.handle.net/11427/6293 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town |
| spellingShingle | Chemistry Smith, Vincent Joseph Physicochemical study of solid Cyclodextrin inclusion complexes of the antithrombotic Ajoene |
| thesis_degree_str | Master's |
| title | Physicochemical study of solid Cyclodextrin inclusion complexes of the antithrombotic Ajoene |
| title_full | Physicochemical study of solid Cyclodextrin inclusion complexes of the antithrombotic Ajoene |
| title_fullStr | Physicochemical study of solid Cyclodextrin inclusion complexes of the antithrombotic Ajoene |
| title_full_unstemmed | Physicochemical study of solid Cyclodextrin inclusion complexes of the antithrombotic Ajoene |
| title_short | Physicochemical study of solid Cyclodextrin inclusion complexes of the antithrombotic Ajoene |
| title_sort | physicochemical study of solid cyclodextrin inclusion complexes of the antithrombotic ajoene |
| topic | Chemistry |
| url | http://hdl.handle.net/11427/6293 |
| work_keys_str_mv | AT smithvincentjoseph physicochemicalstudyofsolidcyclodextrininclusioncomplexesoftheantithromboticajoene |