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Inclusion of alkylparabens in cyclodextrins
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Chemistry
2014
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| _version_ | 1867613240056348672 |
|---|---|
| access_status_str | Open Access |
| author | De Vries, Elise Janine Christl |
| author2 | Caira, Mino R |
| author_browse | Caira, Mino R De Vries, Elise Janine Christl |
| author_facet | Caira, Mino R De Vries, Elise Janine Christl |
| author_sort | De Vries, Elise Janine Christl |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/6302 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:58.612Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Chemistry |
| publisherStr | Department of Chemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/6302 Inclusion of alkylparabens in cyclodextrins De Vries, Elise Janine Christl Caira, Mino R Nassimbeni, Luigi R Chemistry Includes bibliographical references. The aim of this thesis was to prepare crystalline inclusion complexes with cyclodextrins (CDs), as hosts, and drugs, as guests, characterise them using various methods and attempt to elucidate their structures by X-ray diffraction methods to establish the detailed mode of drug inclusion in the solid state. Cyclodextrins and their derivatives have a low polarity central void formed by linked glucose residues of varying numbers. This annular cavity is able to encapsualte low molecular weight molecules and is therefore responsible for the great interest in CDs in host-guest chemistry. In addition, inclusion of drug molecules in cyclodextrins can significantly improve aspects of their performance, such as increased aqueous solubility and dissolution rates which lead to their increasing application in the pharmaceutical industry. 2014-08-13T14:26:07Z 2014-08-13T14:26:07Z 2003 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/6302 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town |
| spellingShingle | Chemistry De Vries, Elise Janine Christl Inclusion of alkylparabens in cyclodextrins |
| thesis_degree_str | Doctoral |
| title | Inclusion of alkylparabens in cyclodextrins |
| title_full | Inclusion of alkylparabens in cyclodextrins |
| title_fullStr | Inclusion of alkylparabens in cyclodextrins |
| title_full_unstemmed | Inclusion of alkylparabens in cyclodextrins |
| title_short | Inclusion of alkylparabens in cyclodextrins |
| title_sort | inclusion of alkylparabens in cyclodextrins |
| topic | Chemistry |
| url | http://hdl.handle.net/11427/6302 |
| work_keys_str_mv | AT devrieselisejaninechristl inclusionofalkylparabensincyclodextrins |