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Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Chemistry
2014
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| _version_ | 1867613155885056000 |
|---|---|
| access_status_str | Open Access |
| author | Munyuki, Gadzikano |
| author2 | Jackson, Graham Ellis |
| author_browse | Jackson, Graham Ellis Munyuki, Gadzikano |
| author_facet | Jackson, Graham Ellis Munyuki, Gadzikano |
| author_sort | Munyuki, Gadzikano |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/6347 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:38.662Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Chemistry |
| publisherStr | Department of Chemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/6347 Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques Munyuki, Gadzikano Jackson, Graham Ellis Venter, Gerhard Chemistry Includes abstract. Includes bibliographical references. The need to come up with new and novel antibiotics that utilize unique mechanisms, to which bacteria cannot generate resistance, was the main motivation of this study. Tyrocidine peptides are non-selective antibiotics that have such properties. However, very limited information is available about their mechanism of action. The aim of this study was to determine the mechanism of action of tyrocidine peptides, tyrocidine A, tyrocidine B and tyrocidine C. 2014-08-13T14:27:33Z 2014-08-13T14:27:33Z 2012 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/6347 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town |
| spellingShingle | Chemistry Munyuki, Gadzikano Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques |
| thesis_degree_str | Doctoral |
| title | Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques |
| title_full | Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques |
| title_fullStr | Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques |
| title_full_unstemmed | Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques |
| title_short | Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques |
| title_sort | molecular mechanism of action of tyrocidine antimicrobial peptides using nmr spectroscopy and computational techniques |
| topic | Chemistry |
| url | http://hdl.handle.net/11427/6347 |
| work_keys_str_mv | AT munyukigadzikano molecularmechanismofactionoftyrocidineantimicrobialpeptidesusingnmrspectroscopyandcomputationaltechniques |