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Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field

Includes bibliographical references (leaves 181-197).

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Main Author: Eisa, Mohamed Eltayeb M
Other Authors: Comrie, Craig
Format: Thesis
Language:English
Published: Department of Physics 2014
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access_status_str Open Access
author Eisa, Mohamed Eltayeb M
author2 Comrie, Craig
author_browse Comrie, Craig
Eisa, Mohamed Eltayeb M
author_facet Comrie, Craig
Eisa, Mohamed Eltayeb M
author_sort Eisa, Mohamed Eltayeb M
collection Thesis
description Includes bibliographical references (leaves 181-197).
format Thesis
id oai:open.uct.ac.za:11427/6528
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:33:51.607Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2014
publishDateRange 2014
publishDateSort 2014
publisher Department of Physics
publisherStr Department of Physics
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/6528 Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field Eisa, Mohamed Eltayeb M Comrie, Craig Conradie, Lowry Pineda-Vargas, Carlos A Physics Includes bibliographical references (leaves 181-197). With the aim of improving the reliability and stability of the beams delivered to the nuclear microprobe at IThemba LABS, as well as optimization of the beam characteristics along the Van de Graaf acceleratore beamlines in general, relevant modifications were implemented. The design and layout of the beamlines in general, relevant modifications were implemented. The design and layout of the beamlines were revised. The beam-optical characteristics through the accelerator, from the ion source up to the analysing magnet directly after the accelerator, were calculated and the design optimised, using the computer codes TRANSPORT, IGUN and TOSCA. The ion source characteristics and optimal operating conditions were determined on an ion source test bench. The measured optimal emittance for 90% of the beam intensity was bout 50π mm mrad for an extraction voltage of 6kV. These changes allow operation of the Nuclear Microprobe at proton energies in the range 1 MeV to 4 meV with beam intensities of tens of a pA at the target surface. The capabilities of the nuclear micropobe facility were evaluated in the improved beamline, with particular emphasis to the characertisation of hard human calcium-rich tissue materials. The process of demineralization in teeth erosion due to exposure to acidic media was investigated in a group of test and control healthy human molar teeth. Samples were cut in cubes of 2014-08-13T20:05:30Z 2014-08-13T20:05:30Z 2005 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/6528 eng application/pdf Department of Physics Faculty of Science University of Cape Town
spellingShingle Physics
Eisa, Mohamed Eltayeb M
Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field
thesis_degree_str Doctoral
title Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field
title_full Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field
title_fullStr Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field
title_full_unstemmed Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field
title_short Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field
title_sort optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field
topic Physics
url http://hdl.handle.net/11427/6528
work_keys_str_mv AT eisamohamedeltayebm optimisationofacceleratoropticsandtheapplicationofnuclearmicroscopytothebiomedicalfield