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Proteoglycan genes and anterior cruciate ligament injury susceptibility
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Human Genetics
2014
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| _version_ | 1867613477711904768 |
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| access_status_str | Open Access |
| author | Mannion, Sasha |
| author2 | September, Alison |
| author_browse | Mannion, Sasha September, Alison |
| author_facet | September, Alison Mannion, Sasha |
| author_sort | Mannion, Sasha |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/6670 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:36:46.668Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Division of Human Genetics |
| publisherStr | Division of Human Genetics |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/6670 Proteoglycan genes and anterior cruciate ligament injury susceptibility Mannion, Sasha September, Alison Collins, Malcolm Medicine Includes abstract. Includes bibliographical references. Genetic variants within genes involved in fibrillogenesis, including a polymorphism in the COL5A1 gene, have previously been associated with anterior cruciate ligament (ACL) injury susceptibility, specifically in females. Proteoglycans have also been implicated in having important functions in fibrillogenesis and maintaining the structural integrity of ligaments. Moreover, their content appears to be lowered in ruptured ACL tissue in comparison to non-ruptured controls. Genes encoding proteoglycans are therefore plausible candidates to be investigated for an association with ACL injury susceptibility. 2014-08-22T10:37:01Z 2014-08-22T10:37:01Z 2013 Master Thesis Masters MSc http://hdl.handle.net/11427/6670 eng application/pdf Division of Human Genetics Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Mannion, Sasha Proteoglycan genes and anterior cruciate ligament injury susceptibility |
| thesis_degree_str | Master's |
| title | Proteoglycan genes and anterior cruciate ligament injury susceptibility |
| title_full | Proteoglycan genes and anterior cruciate ligament injury susceptibility |
| title_fullStr | Proteoglycan genes and anterior cruciate ligament injury susceptibility |
| title_full_unstemmed | Proteoglycan genes and anterior cruciate ligament injury susceptibility |
| title_short | Proteoglycan genes and anterior cruciate ligament injury susceptibility |
| title_sort | proteoglycan genes and anterior cruciate ligament injury susceptibility |
| topic | Medicine |
| url | http://hdl.handle.net/11427/6670 |
| work_keys_str_mv | AT mannionsasha proteoglycangenesandanteriorcruciateligamentinjurysusceptibility |