Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Risk of malignancy in patients with inflammatory bowel disease treated with Azathioprine or 6-mercaptopurine : the Cape Town experience
Includes bibliographical references (leaves 55-63).
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Public Health and Family Medicine
2014
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613218950610944 |
|---|---|
| access_status_str | Open Access |
| author | Setshedi, Mashiko |
| author2 | Myer, Landon |
| author_browse | Myer, Landon Setshedi, Mashiko |
| author_facet | Myer, Landon Setshedi, Mashiko |
| author_sort | Setshedi, Mashiko |
| collection | Thesis |
| description | Includes bibliographical references (leaves 55-63). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/9317 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:39.476Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Public Health and Family Medicine |
| publisherStr | Department of Public Health and Family Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/9317 Risk of malignancy in patients with inflammatory bowel disease treated with Azathioprine or 6-mercaptopurine : the Cape Town experience Setshedi, Mashiko Myer, Landon Watermeyer, Gill Public Health Includes bibliographical references (leaves 55-63). The benefits of the use of Azathioprine (AZA) and its metabolite 6-mercaptopurine (6-MP) in the treatment of Inflammatory Bowel Disease (IBD) are well established. However, concern regarding the long-term use of these agents in the induction of certain malignancies particularlty lymphoma and skin cancer has been reported in renal transplant and rheumatoid arthritis patients. In IBD patients hoever, several retropsective and prospective studies have been conducted (including two meta-analyses) with divergent results. The primary objective of this study was to compare the incidence of cancer in IBD patients treated with AZA/6BMP with those not treated. Secondary objectives were to assess if skin cancer had a higher incidence of occurrence than other cancers, and to determine the independent risk factors associated with cleveloping any malignancy. 2014-11-07T10:10:15Z 2014-11-07T10:10:15Z 2008 Master Thesis Masters MPH http://hdl.handle.net/11427/9317 eng application/pdf Department of Public Health and Family Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Public Health Setshedi, Mashiko Risk of malignancy in patients with inflammatory bowel disease treated with Azathioprine or 6-mercaptopurine : the Cape Town experience |
| thesis_degree_str | Master's |
| title | Risk of malignancy in patients with inflammatory bowel disease treated with Azathioprine or 6-mercaptopurine : the Cape Town experience |
| title_full | Risk of malignancy in patients with inflammatory bowel disease treated with Azathioprine or 6-mercaptopurine : the Cape Town experience |
| title_fullStr | Risk of malignancy in patients with inflammatory bowel disease treated with Azathioprine or 6-mercaptopurine : the Cape Town experience |
| title_full_unstemmed | Risk of malignancy in patients with inflammatory bowel disease treated with Azathioprine or 6-mercaptopurine : the Cape Town experience |
| title_short | Risk of malignancy in patients with inflammatory bowel disease treated with Azathioprine or 6-mercaptopurine : the Cape Town experience |
| title_sort | risk of malignancy in patients with inflammatory bowel disease treated with azathioprine or 6 mercaptopurine the cape town experience |
| topic | Public Health |
| url | http://hdl.handle.net/11427/9317 |
| work_keys_str_mv | AT setshedimashiko riskofmalignancyinpatientswithinflammatoryboweldiseasetreatedwithazathioprineor6mercaptopurinethecapetownexperience |