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Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores

Includes bibliographical references.

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Bibliographic Details
Main Author: Nair, Shankari
Other Authors: Chibale, Kelly
Format: Thesis
Language:English
Published: Department of Chemistry 2014
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access_status_str Open Access
author Nair, Shankari
author2 Chibale, Kelly
author_browse Chibale, Kelly
Nair, Shankari
author_facet Chibale, Kelly
Nair, Shankari
author_sort Nair, Shankari
collection Thesis
description Includes bibliographical references.
format Thesis
id oai:open.uct.ac.za:11427/9805
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:32:00.945Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2014
publishDateRange 2014
publishDateSort 2014
publisher Department of Chemistry
publisherStr Department of Chemistry
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/9805 Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores Nair, Shankari Chibale, Kelly Chemistry Includes bibliographical references. Malaria stills remains one of the leading causes of death in sub-Saharan Africa, with P. falciparum being the most virulent strain of Plasmodium. Due to the emergence of drug resistance, new antimalarial agents are needed to circumvent this. Similarly, in the treatment of cancer, there is an urgent need for the design and development of new antineoplastic agents. This work describes the design, synthesis and biological evaluation of chromone-aminoquinoline hybrids as potentially new chemotherapeutic agents. 2014-11-28T09:53:50Z 2014-11-28T09:53:50Z 2012 Master Thesis Masters MSc http://hdl.handle.net/11427/9805 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town
spellingShingle Chemistry
Nair, Shankari
Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
thesis_degree_str Master's
title Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
title_full Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
title_fullStr Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
title_full_unstemmed Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
title_short Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
title_sort synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
topic Chemistry
url http://hdl.handle.net/11427/9805
work_keys_str_mv AT nairshankari synthesisandevaluationofhybridcompoundsbasedonantimalarialandanticancerpharmacophores