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Includes bibliographical references.
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Department of Chemistry
2014
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| _version_ | 1867613180765667328 |
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| access_status_str | Open Access |
| author | Nair, Shankari |
| author2 | Chibale, Kelly |
| author_browse | Chibale, Kelly Nair, Shankari |
| author_facet | Chibale, Kelly Nair, Shankari |
| author_sort | Nair, Shankari |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/9805 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:00.945Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Chemistry |
| publisherStr | Department of Chemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/9805 Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores Nair, Shankari Chibale, Kelly Chemistry Includes bibliographical references. Malaria stills remains one of the leading causes of death in sub-Saharan Africa, with P. falciparum being the most virulent strain of Plasmodium. Due to the emergence of drug resistance, new antimalarial agents are needed to circumvent this. Similarly, in the treatment of cancer, there is an urgent need for the design and development of new antineoplastic agents. This work describes the design, synthesis and biological evaluation of chromone-aminoquinoline hybrids as potentially new chemotherapeutic agents. 2014-11-28T09:53:50Z 2014-11-28T09:53:50Z 2012 Master Thesis Masters MSc http://hdl.handle.net/11427/9805 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town |
| spellingShingle | Chemistry Nair, Shankari Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores |
| thesis_degree_str | Master's |
| title | Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores |
| title_full | Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores |
| title_fullStr | Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores |
| title_full_unstemmed | Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores |
| title_short | Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores |
| title_sort | synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores |
| topic | Chemistry |
| url | http://hdl.handle.net/11427/9805 |
| work_keys_str_mv | AT nairshankari synthesisandevaluationofhybridcompoundsbasedonantimalarialandanticancerpharmacophores |