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Pattern of prescription of anti-hypertensive medications in a tertiary health care facility in Abuja, Nigeria.

Introduction: Marked changes have been made in the pharmacotherapy of hypertension over the years. In sub-Saharan Africa, hypertension pharmacotherapy is often thought to include only thiazide diuretics, beta blockers and centrally acting medications and, it is unclear if and how often calcium chann...

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Published: 2013
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LEADER 00000njm a2000000a 4500
001 oai:repository.ui.edu.ng:123456789/10109
042 |a dc 
720 |a Ojji D.B.  |e author 
720 |a Ajayi S.O.  |e author 
720 |a Mamven M.H.  |e author 
720 |a Alfa J.  |e author 
720 |a Albertino D.  |e author 
260 |c 2013 
520 |a Introduction: Marked changes have been made in the pharmacotherapy of hypertension over the years. In sub-Saharan Africa, hypertension pharmacotherapy is often thought to include only thiazide diuretics, beta blockers and centrally acting medications and, it is unclear if and how often calcium channel blockers, angiotensin converting enzyme inhibitors and angiotensin receptor blockers are used. Objective: To examine the anti-hypertensive prescription pattern in a tertiary health centre in Nigeria to determine how it conforms to current guidelines. Method: 590 newly diagnosed hypertensive patients presenting at the Cardiology Unit of University of Abuja Teaching Hospital over a three-year period were studied. Result: Calcium channel blockers were the most frequently prescribed anti-hypertensive medications (66.9% of all cases) and centrally acting medications were prescribed in only 5.01% of cases. Single-pill combination either alone or in combination with other antihypertensive medications were prescribed in 17.3% cases. Of these, calcium channel blocker-based combinations constituted the most frequently used multiple drug combinations. 94.6% of the patients required more than one medication for blood pressure control. Conclusion: Anti-hypertensive pharmacotherapy in Abuja, Nigeria, compares favorably with the current recommendations in the prescription pattern of anti-hypertensive medications. (Ethn Dis. 2013;23[4]:480–483) 
024 8 |a Ethnicity and Disease 23(4) Pp.480-483 
024 8 |a https://repository.ui.edu.ng/handle/123456789/10109 
653 |a Hypertension 
653 |a Pharmacotherapy 
653 |a Sub-Saharan Africa 
245 0 0 |a Pattern of prescription of anti-hypertensive medications in a tertiary health care facility in Abuja, Nigeria.